| 锌对大鼠生殖毒性的影响 |
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| 引用本文： | 魏青,范瑞泉,杨杏芬,陈铁江,邓丽霞,吴大伟,朱伟. 锌对大鼠生殖毒性的影响[J]. 卫生研究, 2003, 32(6): 618-619 |
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| 作者姓名： | 魏青 范瑞泉 杨杏芬 陈铁江 邓丽霞 吴大伟 朱伟 |
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| 作者单位： | 中山大学公共卫生学院,广州,510089 |
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| 摘 要： | 为观察锌摄入对大鼠生殖功能的影响。结果显示 ,连续 60天给予低剂量 12mg kg、中剂量 12 0mg kg的锌可使雄性大鼠精子的数目和精子的活动度升高 ,大鼠生殖功能提高 ,高剂量 2 40mg kg的锌可造成生殖系统损伤 ,致使生殖功能的降低 ,但未见影响子代的生长和发育。提示高剂量的锌对雄性大鼠生殖系统有一定的损伤
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| 关 键 词： | 锌 大鼠 生殖功能 |
| 文章编号： | 1000-8020(2003)06-0618-02 |
| 修稿时间： | 2003-03-02 |
Effect of zinc on reproductive toxicity in rats |
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| Wei Qing,Fan Ruiquan,Yang Xingfen,Chen Tiejiang,et al.. Effect of zinc on reproductive toxicity in rats[J]. Journal of hygiene research, 2003, 32(6): 618-619 |
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| Authors: | Wei Qing Fan Ruiquan Yang Xingfen Chen Tiejiang et al. |
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| Affiliation: | School of Public Health, Zhongshan University, Guangzhou 510089, China. |
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| Abstract: | The purpose of this study was to explore the effect of zinc on reproductive function in rats. The results revealed that the sperm count, sperm motility and reproductive function appeared to be enhanced in male rats by 60 days successive administration of low dose zinc(12mg/kg) or medium dose zinc(120mg/kg), whereas reproductive system damages characterized by lowering of reproductive function would be resulted by high dose zinc(240mg/kg). However, no effect on the growth and development of the second generation was shown, suggesting that the injury was just limited to certain extent. |
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| Keywords: | zinc rat reproductive function |
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