广州地区心血管病患者危险因素与血脂水平的分析

目的 探讨广州地区近年来心血管病患者各危险因素对不同性别、年龄段人群血脂水平的影响。 方法 采用现状研究方法，分析1894例珠江医院心内科住院患者各危险因素与血脂水平的关系。 结果 （1）高血压对女性血脂水平的影响大于男性，女性75岁以上年龄段高血压组的Tch水平显著高于非高血压组，女性65-74岁年龄段及整体高血压组的TG水平显著高于非高血压组。（2）吸烟对男性整体Tch和TG水平的上升有显著作用，尤其男性45-54岁年龄段吸烟组的Tch和LDL-C水平均显著高于对照组。（3）糖尿病显著影响男女两性的TG和HDL-C水平，女性65-74年龄段的LDL-C水平亦显著高于对照组。（4）高尿酸血症（HUA）对血脂异常的作用尤为突出。男性HUA组患者四项血脂指标均与对照组有显著差异，其中对Tch和LDL-C水平的影响主要集中在65-74岁年龄段，对HDL-C水平降低的效应则在75岁以上年龄段，TG水平的显著升高则位于45-54岁，55-64岁和65-74岁三个年龄段。女性整体HUA组的TG水平显著高于对照组，体现在45-54岁及75岁以上年龄两个年龄段；65-74岁年龄段HUA组的LDL-C水平显著高于对照组。 结论 不同性别、年龄段患者的血脂水平存在差异。同时不同危险因素对不同组别患者血脂水平有不同程度的影响。血脂异常的防治应采取更具针对性的措施。

Analysis of correlation between different risk factors and plasma lipid level among patients with cardiovascular disease in Guangzhou

Objective To research different risk factors influence on plasma lipid level among patients with cardiovascular disease of different gender and age ranges in recent years in Guangzhou. Methods According to cross-section study, 1894 patients from the Department of Cardiology of Zhujiang Hospital were selected for analyzing the correlation between different risk factors and plasma lipid level. Results (1) Hypertension is more effective on plasma lipid level in female patients than in male patients. For female patients, the Tch level of hypertension group is significant higher than no-hypertension group in the age range of over 75, also the difference of TG level between hypertension groups and their matched groups are statistically significant both in the age range of 65-74 years and in whole range. (2) Smoking is of great effect on the rise of Tch and TG level in all male patients. Simultaneously, it leads to the rise of Tch and LDL-C level in the age range of 45-54 years in male patients. (3) Diabetes has influence mainly on the level of TG and HDL-C in both sexes. At the same time, the difference of LDL-C level between the diabetic and matched group is significant in the age range of 65-74 for female patients. (4) HUA is the most important effect on dyslipidemia in all risk factors. The difference of all four lipid parameters between two groups are statistical significant in male patients. For female patients, it causes mainly the rising of TG level in two age ranges of 45-54, over 75 and whole female group. Conclusion The differences of blood lipid levels exist in different groups patients. The study also shows that different risk factors have effect on plasma lipid level in varying degrees among different gender patients in different age ranges. The more targeted measures should be taken in order to prevent dyslipidemia among the population.