| 印迹基因SGCE在原发性肝细胞癌中的表达及其意义 |
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| 引用本文： | 董辉,颜华东,梁晓岳,徐长风,朱德东,金维荣.印迹基因SGCE在原发性肝细胞癌中的表达及其意义[J].广东医学,2011,32(4):423-426. |
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| 作者姓名： | 董辉 颜华东 梁晓岳 徐长风 朱德东 金维荣 |
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| 作者单位： | 董辉,金维荣,DONG Hui,JIN Wei-rong(国家人类基因组南方研究中心,上海,201203);颜华东,梁晓岳,徐长风,朱德东,YAN Hua-dong,LIANG Xiao-yue,XU Chang-feng,ZHU De-dong(浙江省宁波市肝病医院,315010) |
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| 摘 要： | 目的 探讨印迹基因SGCE在原发性肝细胞癌中的表达及其意义.方法 构建肝癌组织的基因表达谱文库,并对肝癌和正常肝脏组织基因表达谱的数据进行比较分析,寻找差异表达基因.收集临床组织样本,应用荧光定量PCR方法,检测肝癌和相应癌旁组织中SGCE和PEG10基因的表达水平.结果 基因表达谱数据提示,印迹基因SGCE的表达水平...
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| 关 键 词： | 印迹基因 SGCE PEG10 肝癌 |
Expression and significance of imprinted gene SGCE in hepatocellular carcinoma |
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| DONG Hui,YAN Hua-dong,LIANG Xiao-yue,XU Chang-feng,ZHU De-dong,JIN Wei-rong.Expression and significance of imprinted gene SGCE in hepatocellular carcinoma[J].Guangdong Medical Journal,2011,32(4):423-426. |
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| Authors: | DONG Hui YAN Hua-dong LIANG Xiao-yue XU Chang-feng ZHU De-dong JIN Wei-rong |
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| Institution: | DONG Hui,YAN Hua-dong,LIANG Xiao-yue,XU Chang-feng,ZHU De-dong,JIN Wei-rong.Chinese National Human Genome Center at Shanghai,Shanghai 201203,China |
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| Abstract: | Objective To discuss the expression and significance of imprinted gene SGCE in hepatocellular carcinoma(HCC). Methods Genes differentially expression between HCC and normal liver was analyzed base on the construction of gene expression profiling library of HCC.Clinical samples of HCC and corresponding non-tumorous liver tissues were collected for detection of gene expression of SGCE and PEG10 with real-time PCR. Results Expression of imprinted gene SGCE was up-regulated in HCC,with significant difference co... |
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| Keywords: | SGCE PEG10 |
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