孤独症谱系障碍儿童睡眠障碍发生机制和治疗的研究进展

睡眠障碍是孤独症谱系障碍(autism spectrum disorder,ASD)儿童的常见共病,不仅可能加重ASD儿童自身的某些核心症状,还可能影响康复训练效果。ASD儿童睡眠障碍的确切发生机制目前暂不明确,可能与睡眠调控机制异常、ASD核心症状、共患病、躯体器质性病变、营养状况及用药等因素有关。ASD儿童的睡眠障碍目前暂无特殊有效治疗手段,家长培训联合行为干预是目前推荐的具有循证支持的干预方式。

Research advances on pathogenesis and interventions of sleep disorders for children with autism spectrum disorder

Sleep disorders are commonly reported comorbidities in children with autism spectrum disorder (ASD),which might not only exacerbate the core symptoms of ASD,but also adversely impact the intervention efficacy.The potential mechanism for sleep disorders of ASD is not clear so far,it might be due to the abnormal sleep regulation,ASD core symptoms,the co-occurring comorbidities,medical conditions,nutritional deficiency,and the medications commonly used.There are no specific therapeutic interventions for sleep problems of ASD currently,and parent education combined with behavioral interventions is recommended.