早产原因相关研究热点的文献计量学分析

目的：采用文献计量学方法找出早产原因相关研究的热点问题和研究趋势，对现有研究进行 归类总结并为进一步的研究指明方向。方法：在PubMed中以“Premature Birth”[Mesh] AND“Causality”[Mesh]为 检索词对建库到2019年4月的研究进行检索，利用书目共现分析系统（BICOMB）对检索文献进行数据提取，统 计并确定高频主题词形成词篇矩阵和共现矩阵。用SPSS软件对词篇矩阵进行系统聚类，形成研究热点，基于 分析结果形成战略坐标图。结果：共检索到2 965篇文献，利用BICOMB软件提取3 183个主要主题词和副主题 词，确定高频主题词64个，构成6个关于早产原因以及与早产原因研究密切相关的研究热点，最终形成反应各 研究热点发展趋势的战略坐标图。结论：由战略坐标图可知，关于妊娠合并症及并发症引起的早产，母亲体质 量指数、孕龄、孕次等引起的早产和早产引起的不良母儿结局等研究热点发展较为成熟。相反，关于社会、心 理、遗传及母亲孕期暴露等因素引起的早产的研究发展较不完善，为进一步研究提供了空间。此外，关于早产 诊断技术及预防的研究较为成熟，但与其他研究的联系不够紧密，仍需进一步发展。 [ABSTRACT FROM AUTHOR]

A Bibliometric Analysis of Relevant Research Hotspots about Premature Birth Causality

Objective: To search the hotspots and research trend of premature birth by bibliometric analysis, so as to propose the new directions for further research. Methods:Studies about Premature Birth in PubMed were searched from the establishment to April 2019. Bibliographic Items Co-Occurrence Matrix Builder(BICOMB) was used to extract the retrieved documents. High-frequency MeSH terms were identified to form article Matrix and co-occurrence Matrix. Hierarchical cluster analysis was conducted by SPSS 20.0 to form the hotspots.The strategic diagram was then created. Results:A total of 2 965 papers were retrieved, and 3 183 main MeSH terms were extracted by BICOMB software. Sixty four high-frequency keywords were determined and divided into six relevant research hotspots. Finally, a strategic diagram reflecting the development trend of each research hotspot was formed. Conclusions:The pregnant complications and comorbidities, adverse outcomes of maternal and child caused by premature birth, maternal body mass index, gestational age and parity were well developed as the relevant research hotspots. On the contrary, the factors of society, psychologyand genetics, and the adverse exposure during pregnancy, were not adequately documented, suggesting that these factors could be studied in future. In addition, the researches on the diagnosis and prevention of preterm birth are relatively mature, but the connection with other studies is not close enough and further development is needed.