| 王瓜化学成分研究（英文） |
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| 引用本文： | 陈静,程丽,王富乾,汪选斌,张勇慧,郝新才. 王瓜化学成分研究（英文）[J]. 中国药学, 2020, 29(6): 431-438. DOI: 10.5246/jcps.2020.06.041 |
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| 作者姓名： | 陈静 程丽 王富乾 汪选斌 张勇慧 郝新才 |
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| 作者单位： | 1. 湖北医药学院附属人民医院中医科;2. 武汉市第一医院药学部;3. 华中科技大学同济医学院药学院湖北省天然药物化学与资源评价重点实验室 |
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| 摘 要： | 本文对葫芦科植物王瓜化学成分进行了研究,分离得到1个新化合物, 9个已知化合物。通过波谱解析、理化常数及比对文献数据资料进行结构鉴定,分别为3β-[(E)-caffeoyloxy]-D:C-friedooleana-7,9(11)-dien-29-oicacid(1),cucurbitacin B (2), 23,24-dihydrocucurbitacin B (3), 23,24-dihydrocu-curbitacin D (4), cucurbitacin D (5), cucurbalsaminol A (6),3-epi-isocucurbitacin D (7), curbitacin G (8), cucurbitacin J (9) and cucurbitacin I (10),所有化合物均首次从该植物中分离得到。
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| 关 键 词： | 王瓜 化学成分 三萜化合物 结构解析 |
| 收稿时间： | 2019-09-15 |
Chemical constituents from Trichosanthes cucumeroides |
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| Jing Chen,Li Cheng,Fuqian Wang,Xuanbin Wang,Yonghui Zhang,Xincai Hao. Chemical constituents from Trichosanthes cucumeroides[J]. Journal of Chinese Pharmaceutical Sciences, 2020, 29(6): 431-438. DOI: 10.5246/jcps.2020.06.041 |
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| Authors: | Jing Chen Li Cheng Fuqian Wang Xuanbin Wang Yonghui Zhang Xincai Hao |
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| Abstract: | One new triterpenoid, 3β-[(E)-caffeoyloxy]-D:C-friedooleana-7,9(11)-dien-29-oic acid (1) and nine known triterpenoidsidentified as cucurbitacin B (2), 23,24-dihydrocucurbitacin B (3), 23,24-dihydrocu-curbitacin D (4), cucurbitacin D (5), cucurbalsaminol A (6), 3-epi-isocucurbitacin D (7), curbitacin G (8), cucurbitacin J (9) and cucurbitacin I (10)were purified from Trichosanthes cucumeroides. Their structures were confirmed by spectroscopic data analysis and comparison with previous literature. All compounds were obtained from T.cucumeroides for the first time. |
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| Keywords: | Trichosanthes cucumeroides Chemical constituents Triterpenoid Structural identification |
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