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C反应蛋白测定在慢性阻塞性肺病急性加重期的临床意义
引用本文:石慧芳,陈山,何海武.C反应蛋白测定在慢性阻塞性肺病急性加重期的临床意义[J].中国现代医学杂志,2008,18(10):1448-1450.
作者姓名:石慧芳  陈山  何海武
作者单位:海南省农垦总局医院呼吸内科,海南,海口,570311
摘    要:目的探讨C反应蛋白(CRP)测定在慢性阻塞性肺病(COPD)急性加重期诊治中的临床意义。方法选择COPD急性加重住院患者79例,比较其治疗前后血清CRP水平、白细胞总数(WBC)和肺功能(FEV1%预计值)动态变化情况。结果血清CRP和WBC水平在急性加重期较正常组显著升高(P〈0.01)、治疗缓解组较治疗前明显降低(P〈0.01),未缓解组血清CRP水平无明显变化、WBC较治疗前明显降低(P〈0.05)。治疗前和未缓解组血清CRP阳性率明显高于WBC(P〈0.001),缓解组CRP阳性率明显低于WBC(P〈0.05);结论血清CRP测定可作为评价COPD急性加重期患者感染的客观指标,优于WBC等指标,可作为治疗效果评判的重要标志物。

关 键 词:C反应蛋白  慢性阻塞性肺病  急性加重期  反应  蛋白测定  慢性阻塞性  肺病  急性加重期  临床  意义  obstructive  pulmonary  disease  chronic  acute  patients  标志物  治疗效果  客观指标  感染  住院患者  评价  阳性率  态变化  解组
文章编号:1005-8982(2008)10-1448-03
修稿时间:2008年1月16日

Clinical singnificance of CRP in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease
SHI Hui-fang,CHEN Shan,HE Hai-wu.Clinical singnificance of CRP in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease[J].China Journal of Modern Medicine,2008,18(10):1448-1450.
Authors:SHI Hui-fang  CHEN Shan  HE Hai-wu
Institution:SHI Hui-fang,CHEN Shan,HE Hai-wu (Department of Respiratory,Hainan Nongken General Hospital,Haikou,Hainan 570311,P.R.China)
Abstract:Objective] To study the clinical significance of CRP in acute exacerbations of hospitalized patients with chronic obstructive pulmonary disease (COPD) before and after treatment. Methods] The serum CRP levels, the improvement of pulmonary function (FEV1%) and the gross of white blood cell (WBC) were detected of 79 inpatients with acute exacerbations of COPD before and after 2 weeks treatment. Results] Before treatment, the levels of serum CRP and WBC were significantly lower than that of normal subjects ...
Keywords:C-reactive protein  chronic obstructive pulmonary disease  acute exacerbations  
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