Endovascular treatment of superior vena cava obstruction in patients with malignancies |
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Authors: | F. Thony D. Moro P. Witmeyer S. Angiolini C. Brambilla M. Coulomb G. Ferretti |
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Affiliation: | (1) Department of Radiology and Medical Imaging, CHU A Michallon, BP 217, F-38043 Grenoble Cedex 09, France, FR;(2) Department of Respiratory Medicine, CHU A Michallon, BP 217, F-38043 Grenoble Cedex 09, France, FR |
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Abstract: | The aim of this study was to report our experience on the management of superior vena cava obstruction (SVCO) secondary to malignant disease, using endovascular procedures. Twenty-six patients with SVCO due to primary or secondary tumors of the lung or the mediastinum, or catheter inserted for treatment of an extra-thoracic neoplasm, had an endovascular therapy which consisted of stenting, angioplasty, thrombo-aspiration or local fibrinolysis. Immediately after the procedure, rapid relief of symptoms occurred in 24 (90 %) of the patients. The mean Kishi's score decreased from 5.5 to 0.96. Immediate complications included one death related to pericarditis bleeding following fibrinolysis. Three patients relapsed after 20 days, 4 months and 6 months, and needed a second stenting. At 6 months the primary patency rate was 83 % and the secondary patency rate was 89 %. Endovascular treatment of SVCOs is a simple and safe procedure to restore the patency of the superior vena cava in malignant SVCO. It should be indicated in most cases as first-line treatment and performed as early as possible. Received: 8 May 1998; Revision received: 10 August 1998; Accepted: 18 August 1998 |
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Keywords: | : Vena cava Stenosis Obstruction Interventional procedure Neoplasm Grafts and prosthesis Thrombolysis CT |
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