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Two cases of necrotizing crescentic glomerulonephritis with skin lesions |
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| Authors: | Hidekazu Moriya Iwao Nakabayashi Junichirou Nishiyama Aki Ishida Keiji Tazawa Takao Kubota Kunihiko Hino Nobuyuki Yoshizawa |
| Affiliation: | (1) Second Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, 359 Tokorozawa, Saitama, Japan;(2) Department of Public Health, National Defense Medical College, 3-2 Namiki, 359 Tokorozawa, Saitama, Japan |
| Abstract: | Two cases of rapidly progressive glomerulonephritis (RPGN) with skin vasculitis-associated anti-neutrophil cytoplasmic antibody (ANCA) are examined. Both cases showed purpura on the lower legs on admission and subsequently revealed renal or pulmonary vasculitis. One case responded positively to oral prednisolone alone, but the other case showed high ANCA titer and renal—pulmonary vasculitis. We discuss the diversity of clinical symptoms and the titer of antibody-associated vasculitis. |
| Keywords: | Anti-neutrophil cytoplasmic antibody skin lesion vasculitis relapse glomerulonephritis |
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