| 注射用加替沙星与头孢曲松钠配伍的稳定性考察 |
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| 引用本文： | 杨继章,杨树民,刘瑞琴,赵伟娜. 注射用加替沙星与头孢曲松钠配伍的稳定性考察[J]. 中国医院药学杂志, 2005, 25(3): 256-257 |
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| 作者姓名： | 杨继章 杨树民 刘瑞琴 赵伟娜 |
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| 作者单位： | 1. 河北医科大学第一医院,河北,石家庄,050031
2. 河北医科大学药学院2000级,河北,石家庄,050017 |
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| 摘 要： | 目的:考察注射用加替沙星与头孢曲松钠在5%葡萄糖注射液和0.9%氯化钠注射液中配伍的稳定性.方法:在室温(22 ℃),观察两药配伍后的外观、pH值变化,并用紫外分光光度法测定加替沙星和头孢曲松钠的含量.结果:两药配伍后,4 h内的含量、pH值及外观均无明显变化.结论:两药可配伍使用,但应在4 h内用完.
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| 关 键 词： | 加替沙星 头孢曲松钠 配伍 稳定性 紫外分光光度法 |
| 文章编号： | 1001-5213(2005)03-0256-02 |
| 修稿时间： | 2004-08-11 |
A study on the compatibility of gatifloxacin for injection with ceftriaxone sodium for injection |
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| YANG Ji-zhang,YANG SHU-MIN,LIU Rui-qin,ZHAO Wei-na. A study on the compatibility of gatifloxacin for injection with ceftriaxone sodium for injection[J]. Chinese Journal of Hospital Pharmacy, 2005, 25(3): 256-257 |
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| Authors: | YANG Ji-zhang YANG SHU-MIN LIU Rui-qin ZHAO Wei-na |
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| Abstract: | OBJECTIVE To study the compatibility of gatifloxacin for injection with ceftriaxone sodium for injection in 5% glucose injection and in 0.9% sodium chloride injection .METHODS At room temperature for 8 hours, the content of gatifloxacin sodium and ceftriaxone was determined by UV spectrophotometry and the change in appearance, pH was observed.RESULTS No significant change of these parameters was found in 4 hours.CONCLUSION Gatifloxacin for injection can be mixed with ceftriaxone sodium for injection in 5% glucose injection and in 0.9% sodium chloride injection, but must be injected during 4 hours. |
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| Keywords: | gatifloxacin ceftriaxone compatibility stability UV spectrophotometry |
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