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Macrolide-resistant Bordetella pertussis infection in newborn girl, France |
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| Authors: | Guillot Sophie Descours Ghislaine Gillet Yves Etienne Jérome Floret Daniel Guiso Nicole |
| Affiliation: | Institut Pasteur, Paris, France |
| Abstract: | A macrolide antimicrobial drug was administered to a newborn with cough. On day 23 of hospitalization, macrolide-resistant Bordetella pertussis was isolated from nasopharyngeal aspirates. DNA sequencing and PCR-restriction fragment length polymorphism showed a 2047 A-to-G mutation in the 3 copies of the 23S rRNA gene. Monitoring for macrolide resistance is essential in infants <6 months of age. |
| Keywords: | Bordetella pertussis bacteria whooping cough antibacterial drugs antimicrobial resistance macrolide resistance respiratory infections newborn infants children adolescents France |
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