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国产狭叶番泻叶的化学成分研究
引用本文:何文斐,路金才,于晓敏,丁友梅. 国产狭叶番泻叶的化学成分研究[J]. 中药材, 2007, 30(9): 1082-1084
作者姓名:何文斐  路金才  于晓敏  丁友梅
作者单位:1. 温州医学院药学院,浙江温州,325035
2. 沈阳药科大学中药学院,辽宁沈阳,110016
基金项目:浙江省温州市科技局资助项目
摘    要:目的:研究国产狭叶番泻叶Cassia angustifolia Vahl的化学成分,积累对照品,以便系统比较国产与进口狭叶番泻叶内在质量的异同,更好的开发利用国产番泻叶。方法:利用溶剂提取法和各种色谱方法进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:分离鉴定了6个化合物:胆甾醇(Cholesterol,Ⅰ),山柰酚-3-芸香糖苷(Kampferol-3-rutinoside,Ⅱ),1,6-二羟基-3-甲基-xanthone-8-羧酸(Calyxanthone,Ⅲ),3-甲氧基-4-羟基苯甲酸(3-methoxy-4-hydorxy-benzoic acid,Ⅳ),对二甲氨基苯甲醛(P-dimethylaminobenzaldehyde,Ⅴ),3,4-二羟基苯甲酸(3,4-dihydroxybenzoic acid,Ⅵ)。结论:6个化合物均为首次从该植物中分离得到。

关 键 词:狭叶番泻叶  化学成分
文章编号:1001-4454(2007)09-1082-03
修稿时间:2007-03-02

Studies on Chemical Constituents of Leaves of Cassia angustifolia
HE Wen-fei,LU Jin-cai,YU Xiao-min,DING You-mei. Studies on Chemical Constituents of Leaves of Cassia angustifolia[J]. Journal of Chinese medicinal materials, 2007, 30(9): 1082-1084
Authors:HE Wen-fei  LU Jin-cai  YU Xiao-min  DING You-mei
Affiliation:1. Wenzhou Medical College, Wenzhou 325035, China ; 2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:OBJECTIVE: To study the chemical constituents of the leaves of Cassia angustifolia Vahl. METHODS: Solvents extraction and various chromatographic methods were applied to separate and purify its constituents. The structures were elucidated on the basis of chemical evidence and spectral analysis. RESULTS: Six compounds were obtained and identified as cholesterol (I), kampferol-3-rutinoside (II), calyxanthone (III), 3-methoxy-4-hydroxy-benzoic acid (IV), p-dimethylaminobenzaldehyde (V), 3,4-dihydroxybenzoic acid (VI). CONCLUSION: Six compounds ( I -VI) are obtained from this plant for the first time.
Keywords:Cassia angustifolia Vahl  Chemical constituents
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