2013-2015年广安门医院南区门诊抗菌药物使用情况分析

目的：分析中国中医科学院广安门医院南区门诊抗菌药物的使用情况。方法调取广安门医院南区2013—2015年门诊抗菌药物的相关信息，对剂型、销售金额、用药频度（DDDs）、日均费用（DDC）及药品排序比（B/A）进行统计分析。结果抗菌药物类别以β-内酰胺类为主，其次是大环内酯类和喹诺酮类。2013—2015年 DDDs 排名第1位的均为头孢呋辛酯片。抗菌药物给药途径以口服为主。销售金额排名前20名的品种基本没有变化，头孢地尼、头孢呋辛酯是销售金额排名前2位的品种，且 DDDs 排名前3位的为头孢呋辛酯、头孢地尼、阿莫西林克拉维酸钾，排名顺序各年度略有变化。口服剂型中头孢地尼分散片、盐酸莫西沙星片、头孢克肟颗粒的 DDC 较高。注射剂型中注射用哌拉西林钠舒巴坦钠（4∶1）、盐酸莫西沙星氯化钠注射液、注射用头孢西丁钠、注射用盐酸头孢替安、注射用头孢曲松钠的 DDC 较高。2013年 B/A 为1的只有头孢克肟颗粒，2015年 B/A 为1的品种有伊曲康唑胶囊、盐酸莫西沙星片和头孢曲松注射液。结论广安门医院南区门诊抗菌药物使用基本合理，但仍应加强监督管理。

Analysis on use of antibiotics in outpatient of South of Guang'anmen Hospital from 2013 to 2015

Objective To analyze the utilization of antibiotics in outpatient of South of Guang’anmen Hospital. Methods The utilization of antibacterial drugs in South of Guanganmen’s Hospital from 2013 to 2015 was extracted, and the dosage form, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC) and drug sequence ratio (B/A) were analyzed statistically. Results Most antibiotics were β-lactams, and then were macrolides and quinolones. DDDs of Cefuroxime Axetil Tablets always ranked the first. Oral administration was the most administration route. The variety of antimicrobical drugs with top 10 consumption sum did not change. Consumption sum of cefdinir and cefuroxime axetil ranked top 2. DDDs of cefuroxime axetil, cefdinir, amoxicillin, and clavulanate potassium ranked top 3, while each year there was a slight change in ranking order. DDC of Cefdinir Dispersible Tablets, Moxifloxacin Hydrochloride Tablets, and Cefixime Granules in oral drugs were high. DDC of Piperacillin Sodium and Sulbactam Sodium for injection (4∶1), Moxifloxacin Hydrochloride and Sodium Chloride Injection, Cefoxitin Sodium for injection, Cefotiam Hydrochloride for injection, and Ceftriaxone Sodium for injection were high. Only B/A of Cefixime Granules was equal to 1 in 2013. B/A of Itraconazole Capsules, Moxifloxacin Hydrochloride Tablets, and Ceftriaxone Injection were equal to 1 in 2015. Conclusion The utilization of antimicrobial drugs is basically reasonable in outpatient of South of Guang’anmen Hospital, but they still needs further efforts to strengthen the management.