动脉灌注化疗联合放疗治疗晚期食管癌的临床研究

目的研究和探讨动脉灌注化疗联合放射治疗晚期食管癌的临床价值。方法将56例晚期食管癌患者随机分为单纯放射治疗组和动脉灌注化疗联合放疗治疗组,并在治疗后进行随访,观察临床疗效,评价治疗效果。结果综合治疗组的1、2、3年生存率分别为64.3%、50.0%、39.3%,单纯放射治疗组的1、2、3年生存率分别为46.4%、32.1%、21.4%,两组间生存率差异有显著性意义(P<0.05)。两组的毒副作用相似无显著性差异。结论动脉灌注联合放射治疗是治疗晚期食管癌的一种安全、可靠、疗效满意的治疗方法。

Arterial infusion chemotherapy combined with radiotherapy in advanced stage esophageal carcinoma of clinical effectiveness research

Objective To investigate the clinical research and effectiveness in arterial infusion chemotherapy combined with radiotherapy in advanced stage esophageal carcinoma of clinical effectiveness research.Methods Total of 56 patients of middle or advanced stage esophageal carcinoma divided into two groups,group arterial infusion chemotherapy combined with radiotherapy and group pure radiotherapy.At cure the be over hereafter,moreover follow by regular visits to watch the clinical curative effect,evaluate treating effect.Results The synthesis therapy groups the 1-,2-,and 3-year survival rate were 64.3%,50.0% and 39.3%,radiotherapy purely to therapy groups the 1-,2-,and 3-year survival rate were 44.6%,32.1% and21.4%,Two groups of living rate possess significance sense (P<0.05).There was no marked difference in incidence rate of poisonous by reaction between the two groups.Conclusion Arterial infusion chemotherapy combined with radiotherapy therapy in advanced stage esophageal carcinoma is one kind safe and ideal of means.