| 可逆性后部白质脑病综合征的发病机制及研究进展 |
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| 引用本文： | 杜大勇.可逆性后部白质脑病综合征的发病机制及研究进展[J].实用心脑肺血管病杂志,2014(8):1-3. |
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| 作者姓名： | 杜大勇 |
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| 作者单位： | 天津港口医院神经内科,天津市300456 |
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| 摘 要： | 可逆性后部白质脑病综合征(RPLS)是多种病因引起的神经系统受损临床综合征,目前关于其发病机制主要有以下两种学说:脑过度灌注理论和血管痉挛理论,前者主要包括血管机制、血管内皮损伤机制及免疫机制。该病主要临床表现为头痛、抽搐发作、视觉障碍、意识改变及精神行为异常等;典型的神经影像学改变是大脑半球后部白质水肿,以双侧顶枕叶受累最为多见,具有可逆性。
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| 关 键 词： | 后部白质脑病综合征 疾病特征 发病机制 综述 |
Pathogenesis of Reversible Posterior Leukoencephalopathy Syndrome and Its Progress |
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| DU Da-yong.Pathogenesis of Reversible Posterior Leukoencephalopathy Syndrome and Its Progress[J].Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease,2014(8):1-3. |
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| Authors: | DU Da-yong |
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| Institution: | DU Da-yong (Department of Neurology, Tianjin Port Hospital, Tianjin 300456, China) |
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| Abstract: | Reversible posterior leukoencephalopathy syndrome（ RPLS） is a neurological clinical syndrome caused by a variety of reasons. There are two theories about the pathogenesis of RPLS,including cerebrovascular hyperfusion theory（ vas-cular mechanism,endothelial damage mechanism and immune mechanisms） and cerebral vasospasm theory. The common clini-cal symptoms of RPLS include headache,epileptic attack,visual disorder,consciousness disturbance,psychological and behav-ioral abnormalities,and so on. Typical neurological imaging of RPLS is edema in posterior white matter,mainly involved bilater-al parietal and occipital lobe,which is reversible. |
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| Keywords: | Posterior leukoencephalopathy syndrome Disease attributes Pathogenesis Review |
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