高原和内地枪弹伤后细菌感染的对比研究

目的了解金黄色葡萄球菌(SAU)在高原和内地枪弹伤后的感染情况。方法对同龄幼猪用7.62mm钢心枪弹致伤双后肢,取不同时间的伤后挫伤区组织进行细菌学测定。结果两地枪弹伤感染以SAU为主,受伤处两地SAU污染率分别为48%和18%;SAU在伤后定植成功时间高原为3 h而内地<3 h,SAU在高原大量繁殖速度为12 h 5~6代,内地为3~6 h繁殖4~6代,机体与细菌处于相对稳定平衡的时间高原为48 h,而内地为24 h,两地3~36 h SAU的数量差异具有显著性,36 h后差异不显著。结论SAU是高原枪弹伤后感染的主要细菌,其感染大量繁殖速度较内地慢,感染延迟较明显。

Bacterial Infection after Gunshot Injury in Chongqing and Lasa: A Comparative Study

OBJECTIVE To observe Staphylococcus aureus(SAU) infection at high altitude and plain after gunshot injury. METHODS Used 7.62mm bullets to injure posterior limbs of piglets with the same age.We got contusing tissues in different time after injury,to make bacteriologic examination,identify and make a statistic analysis of SAU. RESULTS The main infection was caused by SAU after gunshot injury in two regions.From contusing tissues in two regions,the rate of contamination caused by SAU in Chongqing and Lasa was 48% and 18%,respectively.The time of SAU colonization was 3 hours at high altitude,and less 3 hours at plain.The velocity of reproduction of SAU at high altitude for 12 hours was 5-6 passages,and at plain was 4-6 passages for 3-6h.The time of remaining relative steady state between tissues and germs was 48 hours at high aititude and 24 hours at plain.The difference of the number of SAU between two regions after injury 3-36 hours was significant,But after 36 hours the difference was unsignificant. CONCLUSIONS At high altitude region,SAU is the main germ that causes contamination after gunshot injury,the velocity of reproduction of SAU is slower than that at plain,the time of infection is delayed obviously.