晚期恶性肿瘤患者抑郁状态对生活质量的影响

 目的　调查恶性肿瘤患者抑郁的发生情况及其生活质量状况。方法　选用Beck抑郁问卷、生活质量问卷对住院的晚期恶性肿瘤患者进行调查，分析Beck抑郁得分与生活质量各因子之间的相关性。结果　共调查230例患者，回收有效问卷213份，95.3 %（203／213）患者存在明显的抑郁症状。Beck抑郁状态评估得分与生活质量问卷的躯体、角色、情绪、认知、社会、恶心呕吐、疼痛、呼吸困难、失眠和厌食因子呈正相关（均P＜0.05），与总健康因子呈负相关（r＝-0.296，P＜0.01）。结论　晚期恶性肿瘤患者存在普遍的抑郁状态，且与生活质量间存在相关性。因此有针对性的给予心理干预，利于减轻患者的抑郁，提高生活质量。

Incidence of depression in patients with advanced malignancy and its effect on quality of life

Objective　To investigate the incidence of depression in patients with advanced malignancy and its effect on quality of life. Methods　Patients with advanced malignancy were evaluated with Beck depression and quality of life questionnaires. The correlation of Beck depression scoring with quality of life was analyzed. Results　A total of 230 in-patients with advanced malignancy were enrolled in this study and 213 copies of valid questionnaire were collected. 95.3 % (203/213) patients had depression. The Beck depression scoring had positive correlation with body, role, mood, cognition, society, vomiting, pain, dyspnea, agrypnia and appetite (all P < 0.05), and had negative correlation with total health factors (r = -0.296, P < 0.01). Conclusion　Depression is prevalent in patients with advanced malignancy and correlated with quality of life. Therefore, psychological interventions are needed to relief depression and improve quality of life.