| GLUT4及瘦素在大鼠非酒精性脂肪性肝病中的作用 |
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| 引用本文： | 鲍秀琦,朱捷,张晓波.GLUT4及瘦素在大鼠非酒精性脂肪性肝病中的作用[J].黑龙江医药科学,2011,34(4):3-4. |
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| 作者姓名： | 鲍秀琦 朱捷 张晓波 |
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| 作者单位： | 佳木斯大学附属第一医院消化一科,黑龙江佳木斯,154003 |
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| 摘 要： | 目的:探讨GLUT4及瘦素在大鼠非酒精性脂肪性肝病(NAFLD)中的作用.方法:64只SD大鼠随机分成正常对照组(32只)和高脂饮食组(32只),每组又分为2用、4周、8周、12用四组,按时间点处死各组大鼠,测定大鼠肝组织中GLUT4的含量、血清瘦素含量、空腹血糖(FBG)、空腹血清胰岛素水平(FIns),现察肝组织病...
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| 关 键 词： | GLUT4 瘦素 非酒精性脂肪性肝病 大鼠 |
Role of GLUT4 and Leptin in development of NAFLD in rats |
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| BAO Xiu-qi,ZHU Jie,ZHANG Xiao-bo.Role of GLUT4 and Leptin in development of NAFLD in rats[J].Heilongjiang Medicine and Pharmacy,2011,34(4):3-4. |
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| Authors: | BAO Xiu-qi ZHU Jie ZHANG Xiao-bo |
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| Institution: | BAO Xiu-qi,ZHU Jie,ZHANG Xiao-bo(The First Affiliated Hospital of Jiamusi University,Jiamusi 154003,China) |
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| Abstract: | Objective:To investigate the change and significance of GLUT4 and Leptin in liver homogenate and blood with nonalcoholic fatty liver disease in rats.Methods:Sixty four rats were randomly assigned to control group and high fat diet group with 32 in each.Each group was divided into four subgroups: 2-week,4-week,8-week and 12-week groups.The rats of all groups were killed at the right time.The liver GLUT4 level,blood Leptin level,FGP,FINS and IRI were detected,and then the histological changes were observed un... |
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| Keywords: | GLUT4 Leptin NAFLD rat |
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