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Internet-delivered exposure therapy versus internet-delivered cognitive behavioral therapy for panic disorder: A pilot randomized controlled trial
Affiliation:1. Solli District Psychiatric Centre (DPS), Nesttun, Norway;2. Department of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway;3. Department of Behavioural Medicine, University of Oslo, Oslo, Norway;4. Department of Psychosocial Science, University of Bergen, Norway og Optentia, the Vaal Triangle Campus of the North-West University, Vanderbijlpark, South-Africa;5. Institute of Clinical Medicine, University of Oslo, Oslo, Norway;6. Department of Psychosocial Science, University of Bergen, Bergen, Norway;7. Anxiety Disorders Research Network, Haukeland University Hospital, Bergen, Norway;9. Division of Mental Health and Addiction, Oslo University Hospital, Bergen, Norway;10. Bjørgvin District Psychiatric Centre (DPS), Division of Psychiatry, Haukeland University Hospital, Bergen, Norway;1. Center of Mental Health, Department of Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Würzburg, Würzburg, Germany;2. Department of Psychiatry and Psychotherapy, Phillipps-University Marburg, Marburg, Germany;3. Department of Psychology, University of Cologne, Cologne, Germany;4. Department of Clinical Radiology, University Hospital Münster, Münster, Germany;5. Department of Psychiatry and Psychotherapy, University Hospital Münster, Münster, Germany;6. Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité Universitätsmedizin Berlin, Berlin, Germany;7. Institute of Clinical Psychology and Psychotherapy, Department of Psychology, Technische Universität Dresden, Dresden, Germany;8. Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany
Abstract:AimTo compare the efficacy and acceptability of internet-delivered exposure therapy for panic disorder, to multi-component internet-delivered cognitive behavioral therapy (iCBT) that included controlled breathing, cognitive restructuring and exposure.MethodsParticipants with panic disorder, with or without agoraphobia, were randomized to internet-delivered exposure therapy (n = 35) or iCBT (n = 34). Both programs were clinician guided, with six lessons delivered over eight weeks. Outcomes included panic disorder and agoraphobia symptom severity, as well as depression symptom severity, functional impairment and days out of role.ResultsParticipants in both conditions displayed a large reduction in panic disorder symptom severity (ds >1.30) from pre- to post-treatment. Participants in both conditions displayed medium to large reduction in agoraphobia and depression symptom severity, functional impairment and days out of role. Effects were maintained at three- and six-month follow-up. There was no significant difference between the interventions in clinical outcomes, adherence or treatment satisfaction.ConclusionsInternet-delivered exposure therapy appeared to be as acceptable and efficacious as more established iCBT, despite including less strategies. However, a fully powered replication is now needed to compare the two approaches.
Keywords:Panic disorder  Cognitive behavioral therapy  Exposure therapy  Internet-delivered CBT  Agoraphobia
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