Endovascular treatment of symptomatic intracranial atherosclerotic stenosis with low profile visualized intraluminal support stent |
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| Affiliation: | 1. Department of Neurosurgery, Changhai Hospital, Navy Military Medical University, Shanghai 200433, People’s Republic of China;2. Naval Medical Center of PLA, Navy Military Medical University, Shanghai 200050, People’s Republic of China;1. Department of Neurosurgery, Tanushimaru Central Hospital, Kurume, Japan;2. Department of Neurosurgery, Fukuoka University Chikushi Hospital, Chikushino, Japan;1. Department of Neurosurgery, University of Saint Joseph, Beirut, Lebanon;2. Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA;1. The PLA Rocket Force Characteristic Medical Center, the Teaching Hospital of Soochow University, Beijing, China;2. Department of Vascular Neurosurgery, New Era Stroke Care and Research Institute, The PLA Rocket Force Characteristic Medical Center, Beijing, China;3. Department of Neurology, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China;4. Department of Central Laboratory, the PLA Rocket Force Characteristic Medical Center, Beijing, China;1. Department of Neurosurgery, Changshu No.2 People’s Hospital, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, Jiangsu Province, China;2. Department of Radiology, Changshu No.2 People’s Hospital, The Affiliated Changshu Hospital of Xuzhou Medical University, Changshu, Jiangsu Province, China;3. Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China;4. Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China;1. Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;2. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China;1. Department of Neurosurgery, University of Colorado Hospital, Aurora, Colorado, USA;2. Department of Radiology, University of Colorado Hospital, Aurora, Colorado, USA;3. Department of Radiology, University of Louisville, Louisville, Kentucky, USA |
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| Abstract: | ObjectiveSevere intracranial atherosclerotic stenosis has become one of the main causes resulting transient ischemic attack and stroke. This study aimed to evaluate the efficacy and safety of low profile visualized intraluminal support (LVIS) stent in treating symptomatic intracranial atherosclerotic stenosis.MethodsData of 31 patients with at least 70% stenosis treated with LVIS stent in our center were retrospectively collected between July 2017 and November 2020. Further evaluation of lesion characteristics, technical success rate, preoperative complication, clinical and angiographic follow-up outcome, delayed in-stent stenosis were conducted.ResultsStent delivery and deployment were successfully achieved in all 31 patients (100%). 22 cases (71%) were located in anterior circulation and 9 cases (29%) were located in posterior circulation. The mean degree of stenosis lesion before stent deployment was 85.6 ± 9.4%, while after stenting was 11.2 ± 11.8%. One patient suffered from ischemic complication in stenting procedure, and timely delivery of rt-PA successfully recanalized the artery. Clinical follow-up was available in all 31patients (100%) with mean follow-up time 15.0 ± 12.1(3–45) months. No patients experienced the recurrence of stroke or TIA or death after discharge. Angiographic follow-up was available in 21patients (67.7%) with mean follow-up time 11.43 ± 6.8 (6–36) months. 19 patients (90.5%) were stable while 2 patients (9.5%) developed ISR in their last angiographic follow-up. The 2 patients received balloon angioplasty and reached satisfactory results after retreatment.ConclusionThis preliminary study suggests that LVIS stent deployment was a feasible approach in treating intracranial atherosclerotic stenosis with satisfactory procedure success rate, low complication rate and favorable long-term outcome. |
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| Keywords: | LVIS stent Endovascular treatment Intracranial atherosclerotic stenosis Ischemic Stroke |
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