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Cerebrovascular bypass for ruptured aneurysms: A case series
Affiliation:1. Neurorestoration Centre, Department of Neurosurgery, Keck School of Medicine of the University of Southern California, 1333 San Pablo Street, Room B51 McKibben Hall, Los Angeles, CA 90033, USA;2. Department of Neurological Surgery, University of California San Diego, San Diego, CA, USA;1. Tufts University School of Medicine, United States;2. Tufts Medical Center, Department of Neurosurgery, United States;3. Tufts Medical Center, Department of Hematology and Oncology, United States;4. Tufts Medical Center, Department of Internal Medicine, United States;5. Tufts Medical Center, Department of Pathology, United States;6. Tufts Medical Center, CardioVascular Center, United States;7. Tufts Medical Center, Department of Neurology, United States;1. Alanya Alaaddin Keykubat University, Department of Neurology, Antalya/Alanya, Turkey;2. Alanya Alaaddin Keykubat University, Department of Psychiatry, Antalya/Alanya, Turkey;3. Istanbul Medipol University, Restorative and Regenerative Medicine Center, Istanbul, Turkey;4. Alanya Alaaddin Keykubat University, Department of Radiology, Antalya/Alanya, Turkey;5. Istanbul Medipol University, Department of Neurology, Istanbul, Turkey;6. Istanbul Sancaktepe Research Hospital, Department of Rhinology, Istanbul, Turkey;1. Neurology Department, Soroka University Medical Center, Beer-Sheva, Israel;2. Radiology Institute, Soroka University Medical Center, Beer-Sheva, Israel;3. Research Institute, Soroka University Medical Center, Beer-Sheva, Israel;1. Division of Spinal Surgery/Departments of Orthopaedic and Neurosurgery, NYU Medical Center, NY Spine Institute, New York, NY, USA;2. Department of Orthopaedic Surgery, NYU Langone Orthopedic Hospital, New York, NY, USA;3. Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, USA;1. Dept. of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;2. Dept. of Neurosurgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;3. Neuroscience Interdisciplinary Graduate Program, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;4. Dept. of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Abstract:In patients with aneurysmal subarachnoid hemorrhage (aSAH) unfavorable for endovascular or traditional open surgical techniques, surgical revascularization strategies comprise one of remaining limited options. There is nonetheless a paucity of data on the safety and efficacy of bypass in aSAH. In this study, we aimed to investigate complications and outcomes in a cohort of patients with aSAH treated with bypass. A prospective single-surgeon database of consecutive patients treated for aSAH between 2013 and 2018 was retrospectively analyzed. Complications and functional status at discharge were recorded and analyzed for the patients that underwent bypass surgery. Forty patients with aSAH were treated with bypass surgery (23 extracranial-intracranial; 17 intracranial-intracranial). All-cause perioperative mortality was 13% (6 patients). At discharge and at mean 14-month follow up, respectively, 16/40 (40%) and 16/25 (64%) of patients achieved a Glasgow Outcome Score of 4–5. All-cause, in-hospital complications occurred in 28 patients (70%), of which any ischemic complication occurred in 20 patients (50%), 7 (18%) being open surgical complications. This work represents the largest modern series of bypass for aSAH to date. In cases of aSAH unfavorable for endovascular intervention or traditional open surgical techniques, bypass remains a viable option in this complex group of patients.
Keywords:Aneurysm  Bypass  Cerebral revascularization  Complications  Outcomes  Subarachnoid hemorrhage
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