Relaxin concentrations in exoembryonic fluids during the first trimester |
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| Authors: | Johnson, M.R. Jauniaux, E. Jurkovic, D. Sannino, P. Campbell, S. Nicolaides, K.H. |
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| Affiliation: | 1Department of Academic Obstetrics and Gynaecology Chelsea, London SW10 9NH, UKWestminster Hospital 369 Fulham Road, London SW10 9NH, UK 2Department of Obstetrics and Gynaecology Denmark Hill, London SE5 8RX, UK 3Harris Birthright Centre for Fetal Medicine, King's College Hospital Denmark Hill, London SE5 8RX, UK |
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| Abstract: | In 15 women undergoing therapeutic termination of pregnancy(813 weeks), the median concentration of relaxin was1000 ng/l in maternal serum, 122 ng/l in coelomic fluid and9 ng/l in amniotic fluid. Its presence in coelomic fluid suggeststhat relaxin may be present in the fetal circulation and thusbe able to influence embryonic development during the periodof organogenesis. |
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| Keywords: | abortion/amniotic fluid/embryonic development/first trimester/relaxin |
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