Novel variations in the signal peptide region of transforming growth factor beta1 gene in patients with hepatitis: a brief report from India |
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| Authors: | Gupta V Arora R Saha A Dhir A Kar P Bamezai R |
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| Affiliation: | National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India. |
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| Abstract: | Genotypic status of the signal peptide region of transforming growth factor beta1 (TGF-beta1) showed a significant difference in C/C-genotype frequency at +29 position (codon 10) between a range of viral hepatitis patients and controls (P = 0.009, OR = 3.15, CI = 1.29-7.678), contributed by those who were infected with hepatitis B virus (HBV) alone or HBV + hepatitis delta virus (HDV) (P = 0.003, OR = 5.0, CI = 1.78-13.97). |
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