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Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact
Authors:A. A. Toncheva  D. P. Potaczek  M. Schedel  S. W. Gersting  S. Michel  N. Krajnov  V. D. Gaertner  J. M. Klingbeil  A. Franke  C. Winkler  C. Vogelberg  A. von Berg  A. Bufe  A. Heinzmann  O. Laub  E. Rietschel  B. Simma  J. Genuneit  A. C. Muntau  M. Kabesch
Affiliation:1. Department of Pediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany;2. Department of Pediatric Pneumology, Allergy and Neonatology, Hannover Medical School, Hannover, Germany;3. Department of Pediatrics, National Jewish Health, Denver, CO, USA;4. Department of Molecular Pediatrics, Dr. von Hauner Children's Hospital, Ludwig‐Maximilians‐University, Munich, Germany;5. Institute of Clinical Molecular Biology, Christian‐Albrechts‐University Kiel, Kiel, Germany;6. Department of Clinical Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany;7. Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany;8. University Children's Hospital, Technical University Dresden, Dresden, Germany;9. Research Institute for the Prevention of Allergic Diseases, Children's Department, Marien‐Hospital, Wesel, Germany;10. Department of Experimental Pneumology, Ruhr‐University, Bochum, Germany;11. University Children's Hospital, Albert Ludwigs University, Freiburg, Germany;12. Kinder‐ und Jugendarztpraxis Laub, Rosenheim, Germany;13. University Children's Hospital, University of Cologne, Cologne, Germany;14. Children's Department, University Teaching Hospital, Landeskrankenhaus Feldkirch, Feldkirch, Austria;15. Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany;16. University Children's Hospital, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Abstract:
Keywords:bioluminescence energy transfer  childhood asthma  peripheral blood mononuclear cells  protein–  protein interaction  single nucleotide polymorphism
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