| 外周血循环microRNA与糖尿病的研究进展 |
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| 引用本文： | 韩泽平,何金花,黎毓光. 外周血循环microRNA与糖尿病的研究进展[J]. 现代检验医学杂志, 2014, 0(6): 1-5 |
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| 作者姓名： | 韩泽平 何金花 黎毓光 |
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| 作者单位： | 广州市番禺区中心医院检验科,广州511400 |
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| 基金项目： | 广州市番禺区科信局珠江科技新星项目（2013-专15-6.09）. |
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| 摘 要： | 糖尿病日渐成为了当今仅次于心脑血管病和肿瘤的第三类高度威胁人类健康的疾病，研究证明外周血中存在的微小RNA（microRNA，miRNA）与糖尿病的发生与发展密切相关。由于循环 miRNA检测具有无创性、可重复性等自身特性，决定其对各类糖尿病的诊断和预后评估具有广阔的应用前景。该文初步介绍循环 miRNA的来源与特性，特别是国内外研究循环miRNA作为糖尿病诊断标志物的进展，为进一步深入研究奠定基础。
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| 关 键 词： | 循环 微小RNA 糖尿病 |
Role of Circulating MicroRNA in Diabetes Mellitus |
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| HAN Ze-ping,HE Jin-hua,LI Yu-guang. Role of Circulating MicroRNA in Diabetes Mellitus[J]. Journal of Modern Laboratory Medicine, 2014, 0(6): 1-5 |
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| Authors: | HAN Ze-ping HE Jin-hua LI Yu-guang |
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| Affiliation: | (Department of Clinical Laboratory, Panyu Center Hospital in Guangzhou City ,Guangzhou 511400,China) |
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| Abstract: | Diabetes mellitus has become the third threaten diseases second only to cardiovascular disease and tumor.Many re-searches demonstrated that the microRNAs（miRNAs）in blood related to the occurrence and development of diabetes melli-tus.Because of the non-invasion and repeatability of circulating miRNAs,the circulating miRNAs have a broad application prospect of diagnosis and prognosis evaluation for various types of diabetes.This overview arms to introduce the source and characters of circulating miRNA,and also the progress of circulating miRNA related to diabetes mellitus,so as to lay a foun-dation for further research. |
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| Keywords: | circulating microRNA diabetes mellitus |
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