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冠心康片总黄酮含量的测定
引用本文:胡宗礼,黄晓萍,陈珺霞.冠心康片总黄酮含量的测定[J].中国现代应用药学,2009,26(13):1161-1162.
作者姓名:胡宗礼  黄晓萍  陈珺霞
作者单位:韶关学院英东生物工程学院,广东 韶关 512005
摘    要:目的采用分光光度法测定冠心康片中总黄酮的含量。方法以芦丁为标准品建立标准曲线,检测波长为510 nm。结果回归方程为C=-0.001 42 + 0.855 8A,在0.075 1~0.600 4 mg内呈良好线性关系(r=0.999 9),平均加样回收率为99.42%,RSD为1.64%(n=5)。不同批号冠心康片每片总黄酮平均含量为0.363 1 mg。结论该方法简便、准确,适用于冠心康片的质量分析检验。

关 键 词:丙戊酸钠  注射液  高效液相色谱法  含量测定
收稿时间:1/1/1900 12:00:00 AM

Determination of Total Flavonoids Contents from Guanxinkang Tablet
HU Zongli,HUANG Xiaoping,CHEN Junxia.Determination of Total Flavonoids Contents from Guanxinkang Tablet[J].The Chinese Journal of Modern Applied Pharmacy,2009,26(13):1161-1162.
Authors:HU Zongli  HUANG Xiaoping  CHEN Junxia
Abstract:OBJECTIVE To determine the contents of total flavonoids in Guanxinkang tablet by spectrophotometry.METHODS Taking rutin as the control to make standard curve,the detective wavelength was 510 nm.RESULTS Regression equation was C=-0.001 42+0.855 8A(r=0.999 9).The linear concentration was in the range of 0.075 1-0.600 4 mg for rutin.The average recovery was 99.42%,RSD was 1.64%(n=5).The average contents of total flavonoids from Guanxinkang tablet with different numbers was 0.363 1 mg.CONCLUSION The method is simple and accurate,it can be used for quality control of Guanxinkang tablet.
Keywords:Guanxinkang tablet  spectrophotometry  total flavonoids
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