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重症急性胰腺炎早期器官损害的特征及防治
引用本文:傅强,崔乃强.重症急性胰腺炎早期器官损害的特征及防治[J].中国中西医结合外科杂志,2010,16(2):151-154.
作者姓名:傅强  崔乃强
作者单位:1. 天津市南开医院外科重症监护病房,天津,300100
2. 天津市南开医院胆胰疾病诊疗中心,天津,300100
摘    要:目的:回顾性分析2007—2009年我院外科重症监护病房(SICU)收治的病历资料完整的58例重症急性胰腺炎(SAP)并发多器官功能障碍综合征(MODS)病例,总结早期器官功能损害的病变规律及防治经验。方法:所有SAP病人均在我院SICU接受多学科协作中西医结合综合治疗,患者入科后即给予相关监测,按其MODS标准诊断程序,记录入科后不同的时间段(1、3、7、10和14d)里各器官功能障碍的发生情况,统计SAP早期各器官功能障碍的发生率。结果:本组58例中,胃肠道普遍受累(100%),消化道外累及器官损害发生率从高到低顺序为:肺、心、代谢、肾、循环、肝、凝血、脑。严重并发症急性呼吸窘迫综合征20例(34.48%),休克13例(22.41%),肝功损害11例(18.97%),消化道出血10例(17.24%),肾衰竭6例(15.51%),凝血功能异常6例(10.34%),胰腺脑病5例(8.62%),发生时间无明显差异,全组病例14d内死亡8例,病死率13.79%,与死亡密切相关的危险因素为急性呼吸窘迫综合征、急性肾衰竭和休克。结论:重症急性胰腺炎早期MODS器官损害的特征为肺、心、代谢、肾、循环最常受累,其中与死亡密切相关的危险因素为急性呼吸窘迫综合征、急性肾衰竭和休克,中西医结合防治SAP所致多器官功能衰竭疗效显著。

关 键 词:重症急性胰腺炎  多器官功能障碍综合征  中西医结合  防治

Characteristics and Treatment of Organ Impairment in Early Stage of Severe Acute Pancreatitis
Fu Qiang,Cui Naiqiang.Characteristics and Treatment of Organ Impairment in Early Stage of Severe Acute Pancreatitis[J].Chinese Journal of Surgery of Integrated Traditional and Western Medicine,2010,16(2):151-154.
Authors:Fu Qiang  Cui Naiqiang
Institution:Fu Qiang,Cui Naiqiang. Tianjin Nankai Hospital,Tianjin(300100),China
Abstract:Objective To summarize the pattern of pathological changes and experience of prevention and treatment in early organ function impairment of severe acute pancreatitis(SAP).Methods The case data of 58 patients with Sap complicated with multiple organ dysfunction syndrome(MODS) admitted to the surgical intensive care uniot(SICU) were retrospectively analyzed.All patients with SAP received integrated Chinese and Western medicine treatment of multi-disciplinary collaboration.After enrollment,the patients were gi...
Keywords:severe acute pancreatitis(SAP)  multiple organ dysfunction syndrome  integrated Chinese and Western medicine  prevention and treatment  
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