| 乌头属中药成分的构效关系研究进展 |
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| 引用本文： | 王慧玉,孙晖,陆欣,董辉,王喜军.乌头属中药成分的构效关系研究进展[J].世界科学技术-中医药现代化,2011,13(6):1022-1026. |
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| 作者姓名： | 王慧玉 孙晖 陆欣 董辉 王喜军 |
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| 作者单位： | 黑龙江中医药大学药学院 |
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| 基金项目： | 国家中医药管理局中医药行业科研专项（200807014）：基于代谢组学的有毒中药毒性机理及解毒方法研究，负责人：王喜军。 |
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| 摘 要： | 根据目前对乌头属中药有效成分的结构与药理作用的关系的研究现状,综述了乌头属中药有效成分的结构与其止痛、抗炎、局部麻醉、强心的药理作用及毒性的关系,为基于增效减毒目的的结构修饰提供参考。
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| 关 键 词： | 乌头属 有效成分 药理作用 构效关系 |
| 收稿时间： | 2010/9/14 0:00:00 |
| 修稿时间： | 2011/12/18 0:00:00 |
Advances in the Research of Structure-Activity Relationship of Components in Aconitum Species |
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| Wang Huiyu,Sun Hui,Lu Xin,Dong Hui and Wang Xijun.Advances in the Research of Structure-Activity Relationship of Components in Aconitum Species[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2011,13(6):1022-1026. |
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| Authors: | Wang Huiyu Sun Hui Lu Xin Dong Hui and Wang Xijun |
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| Institution: | School of Pharmacy, Heilongjiang University of Chinese Medicine, Haerbin 150040, China |
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| Abstract: | Based on the advanced research of effective components of Aconitum species, the relationship between the structure and anti-inflammatory, analgesis, local anesthesia and pharmacological activities was reviewed. This paper may supply basic data for modifying the structure of constituents in Aconitum species for the improvement of effect and decrease of toxicity. |
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| Keywords: | Aconitum species effective components pharmacological activity structure-activity relationship |
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