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分子蒸馏技术在中药油精制及其有效成分富集中的案例研究
引用本文:黄妙玲,唐成志,王小会,黄永平,杨得坡. 分子蒸馏技术在中药油精制及其有效成分富集中的案例研究[J]. 世界科学技术-中医药现代化, 2011, 13(4): 671-675
作者姓名:黄妙玲  唐成志  王小会  黄永平  杨得坡
作者单位:中山大学药学院天然药物与中药研究所 广州 510006;南宁市轻工食品研究所 南宁 530031;南宁市轻工食品研究所 南宁 530031;国家健康科技产业基地/中山市尤利卡天然药物有限公司 中山 528437;中山大学药学院天然药物与中药研究所 广州 510006
基金项目:广东省科技厅广东省产学研结合示范项目(2009B090300276):基于分子蒸馏技术的中药标准提取物研发及其产业化,负责人:杨得坡;广西南宁市科技局科技攻关与新产品试制(200802090B):米糠油提取甾醇的工艺研究,负责人:唐成志。
摘    要:分子蒸馏技术是一种新型高效的液-液分离技术,同时也是精制和保护中药有效成分的一种有效途径,特别适用于高沸点、热敏性及易氧化物的分离和纯化。本文总结了近年来中山大学关于中药油精制的分子蒸馏技术研究,并提供了3个案例:米糠油中植物甾醇的制备研究、广藿香油有效成分的分离纯化以及肉桂油中反式肉桂醛的富集,通过这些典型案例分析,作者探讨了分子蒸馏技术在中药油精制中的应用优势及在中药质量控制中的地位。

关 键 词:分子蒸馏  中药油  精制  富集
收稿时间:2010-04-07
修稿时间:2011-02-16

Case Study for Chinese Herbal Oils Refining and Active Ingredients Enrichment by Molecular Distillation
Huang Miaoling,Tang Chengzhi,Wang Xiaohui,Huang Yongping and Yang Depo. Case Study for Chinese Herbal Oils Refining and Active Ingredients Enrichment by Molecular Distillation[J]. World Science and Technology—Modernization of Traditional Chinese Medicine and Materia Medica, 2011, 13(4): 671-675
Authors:Huang Miaoling  Tang Chengzhi  Wang Xiaohui  Huang Yongping  Yang Depo
Affiliation:Institute of Natural and Traditional Chinese Medicine, School of Pharmaceutical Sciences,Sun Yat-sen University, Guangzhou 510006, China;Nanning Institute of Food and Light Industry Research, Nanning 530031, China;Nanning Institute of Food and Light Industry Research, Nanning 530031, China;Zhongshan Unicare Natural Medicine Co. Ltd., Zhongshan 528437, China;Institute of Natural and Traditional Chinese Medicine, School of Pharmaceutical Sciences,Sun Yat-sen University, Guangzhou 510006, China
Abstract:Molecular distillation is not only an innovative liquid-liquid separation technique but also a good approach for refining and protecting active components of Chinese medicine. It is suitable for separation and purification for materials with high boiling point, heat-sensitivity or easy oxygenation. In this paper, the research works carried out by the Sun Yat-sen University on the molecular distillation technology have been summarized. The threecases are the study on preparation of phytosterol in rice bran oil, on separation and purification of active ingredients in patchouli oil and on enrichment of trans-cinnamaldehyde in cinnamon oil. These classical cases were studied to illustrate the practical advantages and status of molecular distillation in Chinese herbal oils refining and quality control of Chinese medicine.
Keywords:Molecular distillation   Chinese herbal oils   refining   enrichment
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