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中药难溶性药物注射给药配方策略
引用本文:刘瑞新,史新元,乔延江.中药难溶性药物注射给药配方策略[J].世界科学技术-中医药现代化,2010,12(5):793-797.
作者姓名:刘瑞新  史新元  乔延江
作者单位:北京中医药大学中药学院 北京 100102; 河南中医学院第一附属医院药学部 郑州 450000;北京中医药大学中药学院 北京 100102;北京中医药大学中药学院 北京 100102
基金项目:国家中医药管理局中医药行业科研专项(200708006):符合中药特点的增溶性药用辅料的筛选与评价,负责人:杨明,子课题负责人:乔延江。
摘    要:目的:为中药难溶性药物注射给药配方提供参考。方法:根据对中药难溶性成分的特点及中药注射剂的剂型特点的分析,结合各类增溶技术的特点和规律,制定其配方策略。结果:对各类配方手段进行了系统总结,并给出了简要配方策略。结论:需加快研究符合中药及中药注射剂特点的难溶性药物配方体系。

关 键 词:难溶性药物  增溶  注射给药  中药注射剂配  方策略
收稿时间:2/8/2010 12:00:00 AM
修稿时间:2010/9/25 0:00:00

Formulation Strategy for Injection Administration of Poorly Water-soluble Drug in Traditional Chinese Medicine
Liu Ruixin,Shi Xinyuan and Qiao Yanjiang.Formulation Strategy for Injection Administration of Poorly Water-soluble Drug in Traditional Chinese Medicine[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2010,12(5):793-797.
Authors:Liu Ruixin  Shi Xinyuan and Qiao Yanjiang
Institution:School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China; Dept. of Pharmacy, The First Affiliated Hospital of Henan College of T.C.M., Zhengzhou 450000, China;School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China
Abstract:This work explored the formulation strategy for the injectable administration of insoluble TCM. A formulation strategy was presented based on the characteristics of poorly water-soluble TCM drugs and injections, the characteristic and rule of various solubilizition techniques, as well as a systematic summary of various formulation methods. It was also proposed to strengthened the study on the formulation system of poorly water-soluble drugs, which is consistent with the features of TCM and its injectable preparations.
Keywords:Poorly Water-soluble Drug  Solubilization  Injection administration  T  C  M  Injections  Formulation Strategy
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