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绝经后骨质疏松症中医证候与骨密度相关关系趋势探讨
引用本文:支英杰,谢雁鸣,白文静.绝经后骨质疏松症中医证候与骨密度相关关系趋势探讨[J].世界科学技术-中医药现代化,2011,13(6):960-963.
作者姓名:支英杰  谢雁鸣  白文静
作者单位:中国中医科学院中医临床基础医学研究所
基金项目:国家自然科学基金项目(30873339):基于非齐性Markov model 建立病证结合的绝经后骨质疏松证早期风险评估模型,负责人:谢雁鸣;中国中医科学院基本科研业务费自主选题项目(Z02102):绝经后骨质疏松人群中医综合干预方案评价研究,负责人:支英杰。
摘    要:目的:探讨绝经后骨质疏松症(PMOP)中医证候与骨密度的相关关系。方法:采用流行病学横断面调查,通过有序Logistic 回归判断。结果:绝经年限、BMI(身高体重指数)与证候类型都是影响骨量丢失程度的因素。其中绝经年限越长、BMI 指数越小,发生PMOP 的概率就越大。不同证候类型,发生PMOP 概率是不同的。肾阳虚证相对于血瘀证,发生骨质疏松的概率最大(P <0.001),具有统计学意义。结论:PMOP 的不同证候与骨密度存在着一定的相关性。骨量减少人群多表现为血瘀证,骨质疏松或严重骨质疏松人群多表现为肾阳虚证。患者的不同证候可以作为判断骨量丢失程度的参考指标之一。我们将继续扩大样本量,为进一步剖析绝经后骨质疏松人群的中医证候特点提供更为充分的依据。

关 键 词:骨质疏松症证候绝经
收稿时间:2011/8/26 0:00:00
修稿时间:2011/12/10 0:00:00

Discussion on Correlation between Chinese Medicine Syndrome of Postmenopausal Osteoporosis and Bone Mineral Density
Zhi Yingjie,Xie Yanming and Bai Wenjing.Discussion on Correlation between Chinese Medicine Syndrome of Postmenopausal Osteoporosis and Bone Mineral Density[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2011,13(6):960-963.
Authors:Zhi Yingjie  Xie Yanming and Bai Wenjing
Institution:Institute of Basic Research in Clinical Medicine, Chinese Academy of Medical Sciences, Beijing 100700, China
Abstract:This study was aimed to explore the correlation between Chinese medicine syndromes of postmenopausal osteoporosis (PMOP) and bone mineral density. Epidemiology cross-sectional survey method was used in this study.The results showed that through ordered logistic regression, duration of menopause, body mass index (BMI) and Chinese medicine syndrome types are factors which affect different stages of bone mineral density. Factors such as longer duration of menopause and smaller BMI lead to greater possibility of PMOP occurrence. It is concluded that certain correlation is existed between different Chinese medicine syndromes of PMOP and bone mineral density.Different Chinese medicine syndromes of PMOP can be served as reference indexes in the determination of the degree of bone loss.
Keywords:Osteoporosis  traditional Chinese medicine syndrome  menopause
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