| 血浆总胆汁酸与原发性高血压的关系 |
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| 引用本文： | 林青,许少锋,陈德涛,孙凤皋. 血浆总胆汁酸与原发性高血压的关系[J]. 福建医科大学学报, 2001, 35(2): 171-173 |
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| 作者姓名： | 林青 许少锋 陈德涛 孙凤皋 |
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| 作者单位： | 福建中医学院附属人民医院检验科, |
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| 基金项目： | 福建省教育厅科研基金资助项目!( JA0 0 0 2 5 ) |
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| 摘 要： | 目的 探讨血浆总胆汁酸水平在高血压发病中的作用。方法 采用酶法检测103例高血压患者的血浆总胆汁酸水平，并与45例肝胆疾病患者及50例健康对照组进行比较。结果 原发性高血压患者血浆总胆汁酸水平明显高于继发性高血压患者及对照组；肝胆疾病组血浆叫胆汁酸水平显著高于其他组但血压并不增高。结论 胆汁酸作为11-β羟类固醇脱氢酶的内源性抑制剂，与原发性高血压的发生存在一定的关系。
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| 关 键 词： | 胆汁酸类 盐类 高血压 羟甾类脱氢酶类 |
| 文章编号： | 1000-2235(2001)02-0171-03 |
| 修稿时间： | 2001-01-17 |
Plasma Total Bile Acid in Patients with Essential Hypertension |
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| LIN Qing,XU Shao-feng,CHEN De-tao,et al. Plasma Total Bile Acid in Patients with Essential Hypertension[J]. Journal of Fujian Medical University, 2001, 35(2): 171-173 |
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| Authors: | LIN Qing XU Shao-feng CHEN De-tao et al |
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| Abstract: | Objective To investigate the effect of the plasma total bile acid on the pathophysiology of essential hypertension(EH). Methods The level of plasma total bile acid was determined with enzymatic method in 103 patients with EH. Results The level of plasma total bile acid in patients with EH was significanthy higher than those in the controls(P<0.05) and secondary hypertension(P<0.05). Conclusion Bile acid as an endogenic inhibitor of 11-β-hydroxysteroid dehydrogenase may participate in the pathophysiology of EH and plays an important role in the development of hypertension. |
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| Keywords: | bile acids and sodiums hypertension hydroxysteroid dehydrogenase |
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