Successful Treatment of Chronic Eosinophilic Pneumonia with Anti-IgE Therapy |
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Authors: | Yoo Seob Shin Hyun Jung Jin Hye-Soo Yoo Eui-kyung Hwang Young Hee Nam Young-Min Ye Hae-Sim Park |
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Institution: | Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. |
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Abstract: | Anti-IgE therapy, using recombinant humanized anti-IgE antibodies, is clinically effective in patients with eosinophil-related disorders such as allergic asthma, allergic rhinitis, and chronic urticaria. Chronic eosinophilic pneumonia tends to respond promptly to systemic corticosteroid therapy, however; relapses are common following corticosteroid tapering. We treated two patients (17- and 19-yr-old males) of chronic eosinophilic pneumonia whose symptoms were cough and dyspnea on exertion. The symptoms were recurrent while tapering off corticosteroid. They were treated with anti-IgE antibody without recurrence for 2 yr and 15 months. Here, we first describe clinical experience of the 2 cases of chronic eosinophilic pneumonia. |
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Keywords: | Chronic Eosinophilic Pneumonia Anti-IgE Therapy |
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