胚胎小肠S-100+树突状细胞的组织分布

目的：观察人胚胎小肠树突状细胞(dendritic cells，DCs)的组织分布。方法：应用SABC免疫组织化学法对人胚胎小肠DC的出现时间、分布部位、形态以及数量等进行研究。结果：(1)人胚胎小肠各段S-100^ DC于第9～11W相继出现，主要分布于粘膜固有层，外形不规则，第24W以后，其突起相连逐渐在固有层形成网状结构。(2)回肠集合淋巴小结S-100^ DC以滤泡问区数量最多，其外形相对规则。结论：人胚胎小肠S-100^ DC主要分布于固有层，其数量随胎龄的增加而逐渐增加，而回肠集合淋巴小结S-100DC呈区域性分布，它们与固有层S-DC在形状、大小和数量上有所不同。

Distribution of S-100 protein positive dendritic cells in fetal small intestine

Objective:To observe the distribution of dendritic cells (DCs) in human fetal small intestine. Methods:Using SABC immunohistochemical technique, the initiation,distribution,morphology and quantity of DCs in human fetal small intestine were studied. Results:(1) S-100 +DCs appeared in human fetal small intestine on 9 th -11 th week of gestation,mostly located in the lamina propria (LP). From the 24 th week,S-100 +DCs with irregular shape began to form a reticular network within the lamina propria in some regions. (2) The majority of S-100 +DCs, often with delicate and fewer processes, were located in interfollicular area in Peyer's patches (PP). Conclusion:S-100 +DCs in human fetal small intestine are mainly located in the lamina propria, and increase with fetal age. PP S-100 +DCs distribute regionally, and the shape, size and quantity of PP S-100 +DC are different from those of LP S-100 +DCs.