儿童过敏性紫癜376例临床分析

目的 :探讨儿童过敏性紫癜 (AP)的临床特点。方法 :对 376例过敏性紫癜患儿的发病特点、临床表现、肾损害相关因素及少见症状等方面进行回顾性分析。结果 :发病季节 :第 1、2、3、4季度的发病率依次为 32 .7%、8.77%、6 .38%、5 2 .12 %。诱因 :感染 341例 ,占 90 .5 9% ,食物过敏 18例 ,占 4 .78%。出现肾脏症状 16 3例 ,发生率为 4 3.35 %。结论 :AP发病率以第 1、4季度发病人数较多 ;发病诱因以感染为第 1位 ;AP早期出现较多肾外症状 ,特别是并发少见症状者 ,易发生肾损害 ;以腹痛为首发症状的 AP易误诊为急腹症

Clinical analysis of 376 cases with anaphylactoid purpura

Objective:To study the clinical characteristics of Anaphylactoid purpura(AP).Methods:The 376 cases with AP treated from April,1995 to October,2001 were retrospectively studied and patterns of onset,clinical manifestations,correlated factors of renal damage and the rare symptoms were analysed.Results:Seasons and onset.The percentage of the 1,2,3,4 quarter were 32.7 %,8.77 %,6.38 %,52.12 %respetively.Inducing factors:They were infections(341 cases,90.59 %),allergic food(18 cases,4.78 %).Totauy (163 cases 43.35 %)presented symptoms of renal damage.The pereentages of patients presenting renal damage were 12.67 %,34.34 %,46.55 %,56.47 %,78.32 % for the patients with purpura only,with purpura and joint symptoms,with purpura and gastrointestinal tract symptoms,with all the above symptoms and with purpura and the rare symptoms,respectively( P <0.01).Conclusions:Morbidity of AP was more in the first and the fourth quarter than the other.The most important inducing factor was infection.There were many extrarenal symptoms during early phase in the AP patients.Those with the rare symptoms tended to have renal damage.Those AP whose first symptom was abdominal pain can be misdiagnosed as acute abdominal disease.