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Wnt信号通路与牙胚发育
引用本文:彭栗(综述),叶玲(审校),周学东(审校). Wnt信号通路与牙胚发育[J]. 牙体牙髓牙周病学杂志, 2008, 18(12): 705-708
作者姓名:彭栗(综述)  叶玲(审校)  周学东(审校)
作者单位:四川大学华西口腔医学院
摘    要:牙齿的发生、分化是牙源性上皮与外胚间充质相互诱导、相互作用的结果。牙胚发育过程中复杂的信号调控体系是近年来口腔科学研究领域的难点和热点。现已初步证实Wnt信号通路是参与牙胚发育过程重要的分子信号调控因子。在牙胚发育过程中,随着Wnt信号通路调控机制的阐明,必将为牙再生的研究提供理论基础。该文就近几年对Wnt信号通路与牙胚发育关系的研究作一综述。

关 键 词:信号通路  牙胚发育

Wnt signal pathway and tooth development
PENG Li,YE Ling,ZHOU Xue-dong. Wnt signal pathway and tooth development[J]. Chinese Journal of Conservative Dentistry, 2008, 18(12): 705-708
Authors:PENG Li  YE Ling  ZHOU Xue-dong
Abstract:Mammalian tooth development is largely dependent upon the sequential and reciprocal epithelial-ectomesenchymal interaction.The complicated signal pathway in the process of tooth development has become the hot point in the research field.It has been proved that the Wnt signal pathway is one of the important signal pathways to regulate the signal transduction of tooth development.With the improvement of Wnt pathway research,the theory of tooth development will be fully developed in the near future.In this review,emphasis was placed on the relationship between tooth development and the role of Wnt signal pathway.
Keywords:Wnt
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