2010年新疆生产建设兵团肿瘤登记地区恶性肿瘤疾病负担研究

目的 了解新疆生产建设兵团（简称兵团）肿瘤登记地区恶性肿瘤死亡情况及疾病负担，为肿瘤防治提供依据。方法 收集2010年兵团肿瘤登记地区（第七师、第八师）恶性肿瘤发病资料和死亡资料，利用死亡率（mortality）、潜在减寿年（potential years of life lost,PYLL）、伤残调整生命年（disabilityadjusted life year, DALY）包括早死所致的健康寿命损失年（years of lifelost, YLL）和残疾所致的健康寿命损失年（years lived with disability,YLD）评价恶性肿瘤疾病负担。结果 2010年肿瘤登记地区全部恶性肿瘤死亡率为113.36/10万，中标率、世标率分别为58.50/10万、79.05/10万。男性死亡率139.08/10万高于女性死亡率87.13/10万。全部肿瘤PYLL为11 603.5人年， PYLL率为10.05‰，高于兵团2008—2012年死因分析恶性肿瘤平均水平。全部肿瘤DALYs率为13.14/千人、YLDs和YLLs分别为0.83/千人和12.31/千人；男性YLLs为13.50/千人高于女性YLLs 10.88/千人。PYLL率与DALYs率随年龄增加而上升，其中PYLL和PYLL率在40岁之后达到高峰，DALYs率从40岁年龄组开始明显升高，在60～69岁年龄组达到最高，且从65岁开始男性高于女性。2010年女性DALYs/千人高于全国水平。结论 兵团肿瘤登记地区肿瘤疾病负担较重，男性高于女性，中老年人肿瘤疾病负担最高，应加强肿瘤的早诊早治项目，减轻居民肿瘤疾病负担。

Disease Burden of Malignant Neoplasms in Cancer Registries Division of Xinjiang Production and Construction Crops in 2010

Objective To estimate the mortality and disease burden of malignant neoplasms in cancer registries division of Xinjiang Production and Construction Crops (XPCC)in 2010, so as to provide the reference for cancer prevention and control. Methods The cancer registered data of XPCC cancer registries division (7th and 8th Division) in 2010 were collected. Mortality, potential years of life lost(PYLL), disability adjusted life year(DALY) including years of life lost(YLL) and years lived with disability(YLD) were calculated. Results The crude mortality of XPCC cancer registries division in 2010 was 113.36/105, and the age-standardized incidence rates of Chinese population and world population were 58.50/105 and 79.05/105 respectively. The mortality of male(139.08/105) was higher than that of female(87.13/105). PYLL of overall cancer was 11 603.5 person-years. PYLL rate was 10.05‰, higher than that of the average level of XPCC from 2008 to 2012. The overall DALYs rate were 13.14 per thousand capita, YLDs were 0.83 per thousand capita, and YLLs were 12.31 per thousand capita. YLLs rate of male (13.50 per thousand capita) were higher than that of female(10.88 per thousand capita). PYLL rate and DALYs rate were increased with age. PYLL and PYLL rate reached the peak at 40 years old. DALYs rate were gradually increased from 40-year-old age group, and reached the peak at 60-69 years old age group, and PYLL rate and DALYs rate of male were higher than those of female from 65 years old. DALYs rate of female was higher than that of the national average level in 2010. Conclusion The disease burden of malignant neoplasms of XPCC cancer registries division is serious. The burden of male is higher than that of female. The highest peak of disease burden occurs in middle and elderly patients. Early diagnosis and treatment and health education about tumor prevention should be carried out so as to reduce the disease burden of malignant neoplasms.