| 结直肠癌患者外周血循环肿瘤细胞的检测及临床研究进展 |
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| 引用本文： | 孙文洁,章 真. 结直肠癌患者外周血循环肿瘤细胞的检测及临床研究进展[J]. 中国癌症杂志, 2015, 25(11): 854-860. DOI: 10.3969/j.issn.1007-3969.2015.11.003 |
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| 作者姓名： | 孙文洁 章 真 |
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| 作者单位： | 复旦大学附属肿瘤医院放疗科，复旦大学上海医学院肿瘤学系，上海200032 |
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| 摘 要： | 结直肠癌是最常见的恶性肿瘤之一，虽然综合治疗的开展使其疗效有较大改善，但仍有较多患者死于术后的复发和转移。循环肿瘤细胞(circulating tumor cell，CTC)来源于肿瘤组织，与肿瘤转移及预后密切相关。对CTC检测方法及其在结直肠癌中的临床研究进行综述。
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| 关 键 词： | 结直肠癌 循环肿瘤细胞 检测 治疗 |
Research progress on circulating tumor cells and their detection in colorectal cancer |
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| SUN Wenjie,ZHANG Zhen. Research progress on circulating tumor cells and their detection in colorectal cancer[J]. China Oncology, 2015, 25(11): 854-860. DOI: 10.3969/j.issn.1007-3969.2015.11.003 |
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| Authors: | SUN Wenjie ZHANG Zhen |
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| Affiliation: | Department of Radiation Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China |
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| Abstract: | Colorectal cancer is one of the most common malignant tumors. Though the development of multidisciplinary therapy has largely improved the therapy effects, many patients still died of local recurrence and metastases after surgery. Circulating tumor cell (CTC) originates from primary tumor tissues and has a closerelationship with cancer metastases and prognosis. This review summarizes the CTC detection methods and relevant clinical research on CTC in recent years. |
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| Keywords: | Colorectal cancer Circulating tumor cell Detection Therapy |
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