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药物洗脱支架术后冠状动脉造影随访无再狭窄患者光学相干断层成像检查结果分析
引用本文:宋现涛,苑飞,李益先,柳弘,金泽宁,孟康,田锐,陈欣,葛长江,周渊,吕树铮.药物洗脱支架术后冠状动脉造影随访无再狭窄患者光学相干断层成像检查结果分析[J].心肺血管病杂志,2010(Z1):91-92.
作者姓名:宋现涛  苑飞  李益先  柳弘  金泽宁  孟康  田锐  陈欣  葛长江  周渊  吕树铮
作者单位:首都医科大学附属北京安贞医院-北京市心肺血管疾病研究所心内科;
基金项目:北京市科委高科技战略主题计划资助项目(D090600604019); 北京市科技新星计划资助项目(2007A001)
摘    要:Objective:To evaluate neointimal coverage after Drug Eluting Stent implantation without no restenosis during angiographic follow up by using optical coherence tomography(OCT).Methods:18 case enrolled into this project who received angiography follow up and OCT checkout.Results:1.Totally,4709 struts were analyzed and 88.6% were completely covered with neointimal,and 0.7% were partly covered and 8.1% were uncovered.The rate of late malapposition of struts was 2.6%.The average neointimal hyperplasia thickness...

关 键 词:冠状动脉造影  光学相干断层成像  再狭窄  支架植入  血管内膜增生  洗脱  随访  支架术  小梁  药物涂层支架

Evaluation about endothelialization of drug eluting stent without no restenosis during angiographic follow up by using optical coherence tomography
SONG Xiantao,YUAN Fei,LI Yixian,LIU Hong,Jin Zening,MENG Kang,TIAN Rui,Chen Xian,GE Changjiang,ZHOU Yuan,LU Shuzheng.Evaluation about endothelialization of drug eluting stent without no restenosis during angiographic follow up by using optical coherence tomography[J].Journal of Cardiovascular and Pulmonary Diseases,2010(Z1):91-92.
Authors:SONG Xiantao  YUAN Fei  LI Yixian  LIU Hong  Jin Zening  MENG Kang  TIAN Rui  Chen Xian  GE Changjiang  ZHOU Yuan  LU Shuzheng
Institution:SONG Xiantao,YUAN Fei,LI Yixian,LIU Hong,Jin Zening,MENG Kang,TIAN Rui,Chen Xian,GE Changjiang,ZHOU Yuan,LU Shuzheng Department of Cardiology,Capital Medical University Affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China
Abstract:Objective:To evaluate neointimal coverage after Drug Eluting Stent implantation without no restenosis during angiographic follow up by using optical coherence tomography(OCT).Methods:18 case enrolled into this project who received angiography follow up and OCT checkout.Results:1.Totally,4709 struts were analyzed and 88.6% were completely covered with neointimal,and 0.7% were partly covered and 8.1% were uncovered.The rate of late malapposition of struts was 2.6%.The average neointimal hyperplasia thickness was 0.099 mm.2.The rates of uncovered struts,late strut malapposition were different among different types of DES,and so did the average neointimal hyperplasia thickness.3.Compared with DES implantation less than 12 months,the average neointimal hyperplasia thickness increased in the group of DES implantation more than 12 months(0.1183 mm vs 0.0875 mm ;P=0.001),and uncovered struts rate were 1.7% and 6.8%respectively(P<0.05),and late struts malapposition rate were 2.1% and 0.5% respectively(P<0.001).Conclusion:Rate of neointimal coverage over DES at about 16-months follow-up was 90.1%,as the rate of uncoverage was 9.9%.Out study suggests that dual antiplatelet therapy might be continued>16 months after DES implantation.
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