| 采用光学相干断层成像技术评价国产雷帕霉素洗脱支架术内膜覆盖情况 |
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| 引用本文： | 宋现涛,杜梦阳,陈欣,苑飞,周玉杰,吕树铮,陈韵岱.采用光学相干断层成像技术评价国产雷帕霉素洗脱支架术内膜覆盖情况[J].心肺血管病杂志,2010(Z1):79-80. |
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| 作者姓名： | 宋现涛 杜梦阳 陈欣 苑飞 周玉杰 吕树铮 陈韵岱 |
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| 作者单位： | 首都医科大学附属北京安贞医院;北京市心肺血管疾病研究所心内科;北京市心肺血管疾病研究所干部病房;解放军总医院心内科; |
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| 基金项目： | 北京市科委高科技战略主题计划资助项目(D0906006040191); 北京市科技新星计划资助项目(2007A001) |
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| 摘 要： | Objective:Confirming complete neointimal coverage after implantation of drug-eluting stent(DES)is clinically important because incomplete stent coverage is maybe responsible for late thrombosis and sudden cardiac death.Optical coherence tomography(OCT)is a high-resolution(≈10 μm)imaging technique capable of detecting a thin layer of neointimal hyperplasia(NIH)inside DES.Helios stent system(KinheIy Bio-tech Co(Shenzhen).Ltd)is a new generation of sirolimus eluting stents.Methods:Motorized optical coherence t...
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| 关 键 词： | 光学相干断层成像 雷帕霉素 洗脱 抗血小板治疗 支架植入 内膜面积 血管内膜 新生内膜 覆盖率 支架术 |
Evaluation on neointimal coverage of domestic sirolimus eluting stent after implantation for nine months by Optical Coherence Tomography (OCT) |
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| SONG Xiantao,DU Mengyang,CHEN Xin,YUAN Fei,ZHOU Yujie,LU Shuzheng,CHEN Yundai.Evaluation on neointimal coverage of domestic sirolimus eluting stent after implantation for nine months by Optical Coherence Tomography (OCT)[J].Journal of Cardiovascular and Pulmonary Diseases,2010(Z1):79-80. |
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| Authors: | SONG Xiantao DU Mengyang CHEN Xin YUAN Fei ZHOU Yujie LU Shuzheng CHEN Yundai |
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| Institution: | SONG Xiantao,DU Mengyang,CHEN Xin,YUAN Fei,ZHOU Yujie,LU Shuzheng,CHEN Yundai Department of Cardiology,Capital Medical University affiliated Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China |
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| Abstract: | Objective:Confirming complete neointimal coverage after implantation of drug-eluting stent(DES)is clinically important because incomplete stent coverage is maybe responsible for late thrombosis and sudden cardiac death.Optical coherence tomography(OCT)is a high-resolution(≈10 μm)imaging technique capable of detecting a thin layer of neointimal hyperplasia(NIH)inside DES.Helios stent system(KinheIy Bio-tech Co(Shenzhen).Ltd)is a new generation of sirolimus eluting stents.Methods:Motorized optical coherence tomographic pullback was performed at 9-month follow-up to examine consecutive Helios stent mplantations in 10 patients.NIH thickness inside each strut and NIH area percentage inside each cross-section were measured.Results:In total,2063 struts in 296 mm stented segments were analyzed.Overall,NIH thickness were(95.7±66.62)μm,rates of exposed struts was 60.2% and the average NIH area percentage was 5.0618% ± 5.6625%.Conclusion:Our study suggests that dual antiplatelet therapy after Helios stent implantation must be continued at least 9months after DES implantation. |
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