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Development of angioimmunoblastic T-cell lymphoma after treatment of diffuse large B-cell lymphoma: a case report and review of literature
Authors:Yaya Wang  Bailu Xie  Yu Chen  Zhenqian Huang  Huo Tan
Institution:1.Centre of Oncology and Hematology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;2.The Department of Pharmacy, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China;3.The Department of Pathology, Guangdong General Hospital, Guangzhou, China
Abstract:Cases of diffuse large B-cell lymphoma (DLBCL) arising after the initial diagnosis of angioimmunoblastic T-cell lymphoma (AITL) and DLBCL synchronous with AITL have been reported. To date, there is no report on the subsequent development of AITL in patients with DLBCL. Here we presented a rare case of AITL developing six months after the initial diagnosis of DLBCL. In order to investigate the clinical and molecular features of patients with AITL and DLBCL, we also reviewed the literature on AITL patients developing DLBCL, and patients with composite AITL and DLBCL.
Keywords:Angioimmunoblastic T-cell lymphoma  diffuse large B-cell lymphoma  composite lymphoma
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