镍钛记忆合金气管腔内支架的实验研究

报告采用记忆合金支架治疗气管软化的实验研究，７条犬造成气管软化模型后，将支架置入软化部位。气道阻力测定结果表明，该支架能有效地克服气道软化，观察２～６个月，支架全部发生移位。向近端移位的３条犬，最终全部出现肉芽组织增生，阻塞管腔，向远端移位的４条犬中有３条出现理想的结果，即正常气管上皮爬过重建光滑的气管腔，支架的合金丝逐渐被纤维包膜所包绕，作者认为：对于临床上没有理想治疗方法的远端气管软化，该方法

Nitinol Alloy Intraluminal Tracheal Stent Used in Treatment of Tracheomalacia:Experimental Study

The authors introduce an animal study of the feasibility in using nitinol alloy intraluminal tracheal stent(Ni-Ti ITS) in treatment of trachomalaica.Altogether 7 stents were successfully implanted into the malacia part of the trachea of 7 mongrels.During 2 to 6 month observation period, chest roentgenography,tracheal endoscopy,airway resistance pathologic section of the trachea etc,(Raw) were studs ed.The experimental results showed: the collapsed airswy could be strengthened by implanting stent.All stents were found displaced,3 to the subglottic or middle cervical portion of the trachea with severe infection and obstruction by granulations i and 4 to the distal portion, with 1 dog having similar results to the first 3 The results of the remaining 3 dogs were promising and encouraging,the stents being coverd by regenerated ciliated epithelium and surrounded by fibrous capsules.Based on the totality of the data and the observations,a conclusion is reached that:Ni-Ti ITS is promising in treatment of distal tracheomalacia.