美罗培南治疗新生儿继发性腹膜炎疗效分析

目的 探讨应用美罗培南治疗新生儿继发性腹膜炎的疗效.方法 2006年1月至2009年6月我院新生儿外科应用美罗培南治疗24例继发性腹膜炎患儿,并对其疗效予以评价.结果 24例患儿中21例细菌培养阳性,共检出细菌30株.经美罗培南治疗后,21例患儿痊愈.1例放弃治疗,2例死亡.细菌清除率86.7%,临床治愈率及综合治愈率为87.5%,临床疗效与细菌学疗效一致性100%.结论 美罗培南治疗新生儿继发性腹膜膜炎是有效的和安全的.

Analysis of the efficacy of meropenem in treating secondary peritonitis in newborn infant

Objective To investigate the efficiency of meropenem in treating secondary peritonitis in newborn infant. Methods Twenty-four newborn infants with secondary peritonitis were treated by meropenem from January 2006 to June 2009 in Tianjin Childrens Hospital. The therapeutic effects were evaluated in the 24 cases. Results Twenty-one patients revealed positive of germiculture and 30 germ strains were isolated from the culture. After the treatment with meropenem, complete cure were observed in 21 newborns. One case gave up treatment,and the other two died. Overall bacterial clearance rate was 86. 7%. Both the clinical cure rate and the total cure rate were 87.5%. The clinical effect consisted with bacteriological effect. Conclusions Meropenem is effective and safe in the treatment of secondary peritonitis in newborn infant.