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10种常用染发剂的致突变作用研究
引用本文:贺小琼,陈彦红,吴双凤.10种常用染发剂的致突变作用研究[J].昆明医学院学报,2005,26(4):36-39.
作者姓名:贺小琼  陈彦红  吴双凤
作者单位:昆明医学院公共卫生学院,昆明,650031
摘    要:目的:研究检测常用染发剂是否具有致突变作用,为指导消费、保护健康提供科学依据.方法:采用鼠伤寒沙门氏菌/哺乳动物肝微粒体酶试验(Ames试验)对国内外的10种知名品牌染发剂进行致突变性检验.结果:所检测的10种国内外知名品牌染发剂均具有阳性致突变作用,其中8种染发剂具有移码突变致突变作用,2种染发剂同时具有移码突变和碱基置换致突变作用.结论:所检测的染发剂具有致突变作用,可对健康产生危害。

关 键 词:染发剂  突变  Ames试验  遗传毒性
文章编号:1003-4706(2005)04-0036-04
收稿时间:2005-10-10
修稿时间:2005年10月10

Study of the Mutagenicity of 10 Hair Coloring Creams
HE Xiao-qiong,CHEN Yan-hong,WU Shuang-feng.Study of the Mutagenicity of 10 Hair Coloring Creams[J].Journal of Kunming Medical College,2005,26(4):36-39.
Authors:HE Xiao-qiong  CHEN Yan-hong  WU Shuang-feng
Institution:Public Health Faculty of Kunming Medical College, Kunming 650031, China
Abstract:Objective: To examine whether the hair coloring creams have mutagenicity,and to afford scientific data for health protection.Methods: The mutagenicity of the 10 hair coloring creams was tested by salmonella typhimurium/mammals microsomal enzyme test(Ames assay).Results: The 10 hair coloring creams tested in this study were all mutagenic.Of them,8 hair coloring creams were shamshelft mutagens,2 were both shamshelft and base-pair substitution mutagens.Conclusion: The tested hair coloring creams were mutagenic.They were harmful for health.
Keywords:Hair coloring cream  Mutagenicity  Ames assay  Genotoxicity
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