卵巢早衰的病因研究进展

卵巢早衰是指女性在40岁以前因卵巢内卵泡耗竭或卵泡功能障碍而导致的闭经现象。卵巢早衰的发病机制并不明确,涉及染色体异常、免疫因素、体内酶的缺乏、环境应激刺激损伤、促性腺激素传导障碍等。近年来卵巢早衰在人群中的发病率呈上升趋势,且呈现年轻化,严重影响女性患者的生活质量。充分了解卵巢早衰的病因,有助于提高治疗水平,改善患者生活质量。

Progress of study on Pathogenesis of Premature Ovarian Failure

Premature ovarian failure is the phenomenon of amenorrhea caused by ovarian follicles depletion or follicle dysfunction before the age of 40 among women.The pathogenesis of premature ovarian failure is not clear, but it relates to chromosomal abnormalities, immune factors, the lack of enzymes in the body, environmental stress injury, and gonadotropin conduction dysfunction.In recent years, the morbidity of premature ovarian failure is on the rise among people, especially in the young, and it seriously affect the female patients' quality of life.To understand the pathogenesis of premature ovarian failure sufficiently is contribute to improve the level of trement and promote the patients quality of life.