食管癌贲门癌术后生活质量评价和影响因素分析

目的 评价食管癌病人和贲门癌病人的术后生活质量,探讨术后生活质量的影响因素.方法 应用EORTC QLQ问卷表随访119例食管癌和贲门癌术后病人,对其生活质量进行评价.结果 食管癌术后病人的躯体功能、角色功能和总体健康状况评分明显高于贲门癌者(P＜0.05),而疲劳、失眠、进食习惯、体重减轻、反流、呕吐症状评分较贲门癌者低(P＜0.05).食管大部切除组各项评分优于胃近端次全切除组(P＜0.05).手术1年后,病人生活质量改善.发生手术并发症者生活质量较差.结论 食管癌病人的术后生活质量优于贲门癌者,手术方式、术后时间、术后出现并发症可影响病人的生活质量.

Assessment of quality of life of patients who underwent resection for cancer of the esophagus and gastric cardia

Objective To investigate the differences of QoL between patients who underwent surgery for esophageal cancer (EC) and cardiac cancer (CC).Methods The main questionnaire (EORTC QLQ c-30) and the esophageal specific module (EORTC OES24) were used for data collection in 119 patients who underwent esophagectomy for cancer.Results The scores of physical,role functioning and global health status in patients who underwent esophagectomy for EC were higher than those who underwent gastroesophagectomy for CC (P＜0.05).The scores of fatigue,insomnia,appetite loss,declining of physical weight,vomit and reflux symptoms were significantly reduced in patients who underwent EC resection(P＜0.05).The occurrence of surgery-related complications statistically reduced above indices of quality of life (P＜0.05).These indices were significantly improved 1 year after surgery(P＜0.05).Conclusion The quality of life for the patients who had EC resection is significantly superior to that for those who underwent CC resection.Type of surgery,postoperative time,surgery-related complications have influence on the quality of life.