| 动态浊度法定量测定氧氟沙星注射液细菌内毒素含量 |
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| 引用本文： | 邓永坤,李晓林,周健华,许华原,杨得强.动态浊度法定量测定氧氟沙星注射液细菌内毒素含量[J].西南国防医药,2004,14(3):257-258. |
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| 作者姓名： | 邓永坤 李晓林 周健华 许华原 杨得强 |
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| 作者单位： | 解放军第59中心医院药剂科,云南,开远,661600 |
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| 摘 要： | 目的 :建立氧氟沙星注射液细菌内毒素定量测定方法。方法 :应用动态浊度法考察氧氟沙星注射液对鲎试剂反应的干扰。结果 :氧氟沙星注射液 4倍稀释后对鲎试剂反应无干扰。结论 :用动态浊度法定量检测氧氟沙星注射液细菌内毒素含量是可行的。
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| 关 键 词： | 动态浊度法 氧氟沙星注射液 细菌内毒素 |
| 文章编号： | 1004-0188(2004)03-0257-02 |
| 修稿时间： | 2003年12月10 |
Bacterial endotoxin quantiative determination of ofloxacin injection by kinetic turbidimetric technique |
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| DENG Yong-kun,LI Xiao-lin,ZHOU Jian-hua,XU Hua-yuan,YANG De-qiong.Bacterial endotoxin quantiative determination of ofloxacin injection by kinetic turbidimetric technique[J].Medical Journal of National Defending forces in Southwest China,2004,14(3):257-258. |
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| Authors: | DENG Yong-kun LI Xiao-lin ZHOU Jian-hua XU Hua-yuan YANG De-qiong |
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| Institution: | DENG Yong-kun,LI Xiao-lin,ZHOU Jian-hua,XU Hua-yuan,YANG De-qiong.Department of Pharmacology,No.59 Hospital of PLA,Kaiyuan 661600 |
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| Abstract: | Objective:To establish a determination method of bacterial endotoxin content in ofloxacin injection.Methods:Kinetic turbidimetric technique was used to investigate the interference of ofloxacin injection to limulus reagent reaction.Results:The ofloxacin injection after 4 times dilution had no interference to limulus reagent reaction.Conclusion:It is practicable to detect the bacterial endotoxin content in ofloxacin injection by kinetic turbidimetric technique. |
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| Keywords: | kinetic turbidimetric technique ofloxacin injection bacterial endotoxin |
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