| 口腔黏膜下纤维性变S100蛋白表达 |
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| 摘 要： |
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| 关 键 词： | 口腔黏膜下纤维性变 S100蛋白 表达 免疫组织化学 |
Expression of S100 in oral submucose fibrosis] |
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| Xiao-li Xie,Zhan-gui Tang,Zhi-gang Yao. Expression of S100 in oral submucose fibrosis][J]. Bulletin of Hunan Medical University, 2003, 28(4): 388-390 |
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| Authors: | Xiao-li Xie Zhan-gui Tang Zhi-gang Yao |
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| Affiliation: | Department of Stomatology, Xiangya Hospital, Central South University, Changsha 410008, China. |
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| Abstract: | OBJECTIVE: To study the expression of S100 in oral submucose fibrosis(OSF). METHODS: Immunohistochemistry assay was performed on 10 cases of OSF, 10 cases of oral epithelial dysplasia (OED) and 8 cases of normal oral epithelium using monoclonal antibody against S100 protein. RESULTS: S100 did not express in the normal oral muscosal epithelium. The S100 positive nuclear staining was found in 50% of the OSF and OED cases, which was significantly higher than that in the normal oral epithelium (P < 0.05). But the positive staining in the OSF and OED cases had no difference (P > 0.05). CONCLUSION: S100 expression is closely related to the development of OSF and OED. The positive staining expression in the OSF and OED cases is the same. |
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