Assessing disease activity and disease activity indices for inflammatory bowel disease |
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Authors: | Xiao Li Feng Sutherland Lloyd R |
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Affiliation: | (1) Departments of Community Health Sciences and Medicine, University of Calgary, 3330 Hospital Drive NW, T2N 4N1 Calgary, AB, Canada |
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Abstract: | A crucial step in the development of clinical trials to determine the efficacy of various therapies for inflammatory bowel disease (IBD) has been the creation of activity indices. This article reviews the major components and operating characteristics of clinical activity indices commonly used in randomized, controlled trials of IBD therapy. In addition, the paper provides a brief overview of the developmental requirements for any new index. |
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