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Mecanotransduction and Endothelial Cells
作者姓名:S.MULLER  JF. STOLTZ
基金项目:This work was supported by AFCRST-Fance and MOST-China (Pro-gramPRAB02-08) and National Natural Sciences Foundation of China(grantNo.30170241)
摘    要:1 IntroductionAtherosclerosis preferentially occurs in areas of complex blood flow where there are disturbed flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective~(1]). Reports of others and our studies suggest a steady laminar flow decreases some molecules and genes expression of vascular endothelial cells (EC) that may promote atherosclerosis, as well as it can differentially regulate production of many vasoactive factors at the level of gene…

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